The United States of America, As Represented by the Secretary, Department of Health and Human Services

University of Massachusetts

Analiza, Inc.

William Charles Vogt

Christopher V Hollot

Yossi Chait

Joseph Horowitz

Michael Jack Germain

Michael J Germain

Thomas Joshua Pfefer

Congxian Jia

Keith Wear

Brian Garra

The present invention is generally directed to methods and devices for determining dosing for a medical agent. In some embodiments, a mathematical algorithm is employed for computing erythropoiesis-stimulating agents dosing for treating anemia in a subject, e.g., a human subject. Any suitable dosing may be used, e.g., intravenous, subcutaneous, or oral dosing. In some cases, dosing for a wide range of subject types and health conditions can be achieved using the devices and methods disclosed herein.

Methods and devices for determining optimal agent dosages

Novel phantoms are provided herein that can accurately mimic the optical and/or acoustic properties of living tissue. The disclosed phantoms are constructed of one or more polyvinyl chloride plastisol (PVCP) gels comprising a PVC and a binary plasticizer. The phantoms can be used, for example, to calibrate or test an optical and/or acoustic detection system, such as a photoacoustic imaging system or an ultrasound imaging system.

PVCP phantoms and their use

Growing community of inventors

Washington, DC, United States of America

William Charles Vogt