Edwards Lifesciences Corporation

Medtronic Xomed, Inc.

Koninklijke Philips Corporation N.v.

Medtronic, Inc.

Philips Medical Systems (cleveland), Inc.

William Charles Brunnett

Kevin Lee McFarlin

Michael J Scott

Rafael Pintor

August R Yambao

Faisal Kalam

Andrew Phung

David C Hacker

Alison S Curtis

Dwayne S Yamasaki

John Murdock Murphy

Robert K Vaccaro

Carla A Pagotto

Netanel Benichou

Lauren R Freschauf

Emil Karapetian

Qinggang Zeng

Lawrence J Farhat

Gregory I Bak-Boychuk

Harvey H Chen

Christopher J Olson

Carey L Cristea

Cristobal R Hernandez

Alexander J Siegel

James B Hissong

Alexander H Cooper

Wenjeng Li

Matthew A Peterson

Thomas H Chien

Stanton J Rowe

Michael S Ferrell

Rodney Arnold Mattson

Dana A Oliver

Cecil O Lewis

Ronald Bryan Sharpless

Louis A Campbell

Alain F Carpentier

Da-Yu Chang

Glen Thomas Rabito

Kenneth M Adams

Randall Peter Luhta

John F Migliazza

Dustin P Armer

Charles Stanislaus

Sara M Walls

Kevin W Zheng

Maria Charles Vijay Stanislaus

Tino Schuler

Maria Charles Vija Stanislaus

David Reinker

Joshua David Rubin

John A Meyer

Aayush Malla

John N Gardi

Benjamin Morris Rubin

Denise Grant

Anand R Rao

Steven M Ford

Thomas Y Chien

Alex Siegel

Thomas Chien

Micahel S Ferrell

Nancy Khuu

Kevin Mcfarlin

Sonny Yamasaki

John Murphy

Rob Vaccaro

Britt Hissong

Qinggang Zenq

Maria-Charles Stanislaus

Alain Carpentier

Denise G Grant

David M Reiker

David M Reinker

Maria Charles Stanislaus

Benjamin M Rubin

John M Murphy

Dwayne Sonny Yamasaki

James Britton Hissong

Faisai Kalam

Kevin L Mcfarlin

This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.

Valvular insufficiency repair device and method

A method of implanting a prosthetic heart valve at a native tricuspid valve region includes delivering a prosthetic heart valve to the native tricuspid valve region via the inferior vena cava or the superior vena cava and deploying the prosthetic heart valve from a sheath of a delivery apparatus. The prosthetic heart valve includes a radially compressible and expandable frame assembly having an inflow end, an outflow end, and a double-body structure having an annular inner frame and an annular outer frame. The outer frame preferably includes an atrial flange portion configured to contact an atrial face of the native tricuspid valve region. The prosthetic heart valve can further include a plurality of ventricular anchors, each comprising a free end portion and a fixed end portion connected to and extending from the frame assembly at a location spaced from the outflow end of the frame assembly.

Method for replacing a tricuspid valve

Systems of quickly and easily implanting a quick-connect heart valve prosthesis during a surgical procedure are provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.

Expandable prosthetic heart valve safety systems

This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In some implementations, a heart valve leaflet clipping mechanism includes a delivery apparatus and clipping arms. The clipping arms are coupled to the delivery apparatus. The clipping arms are movable between an open position and a closed position. The two clipping arms are biased to the closed position. The delivery apparatus is configured to hold the clipping arms in the open position. The delivery apparatus is configured to allow the clipping arms to move to the closed position to engage native heart valve leaflet tissue.

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.

Methods for rapidly deployable surgical heart valves

A prosthetic remodeling annuloplasty ring for use in tricuspid or mitral valve repairs to provide support after annuloplasty surgery. The annuloplasty ring includes a relatively rigid core extending around an axis that is discontinuous to define two free ends. A suture-permeable interface surrounding the core includes floppy regions adjacent both free ends of the core. Sutures are used to attach the annuloplasty ring to the annulus, including at least one suture through each of the floppy regions to secure the free ends of the ring and minimize the risk of ring dehiscence, or pull through of the sutures through the annulus tissue. The floppy regions may project from each free end into the gap toward each other, be radially enlarged such as paddle-like extensions, or may comprise outwardly lateral extensions at the free ends of the core.

Methods of implanting an annuloplasty ring for reduced dehiscence

Methods of quickly and easily implanting a quick-connect heart valve prosthesis during a surgical procedure are provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.

Methods of safely expanding prosthetic heart valves

Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.

Prosthetic valve for replacing a native mitral or tricuspid valve

Systems for rapidly deployable surgical heart valves

A nerve monitoring system facilitates monitoring an integrity of a nerve.

Method and system for monitoring a nerve

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.

Endotracheal tube apparatus

Growing community of inventors

Mission Viejo, CA, United States of America

William Charles Brunnett