E.i. Dupont De Nemours and Company

Other

William C Seidel

Nicholas Nazarenko

V N Rao

Frank J Weigert

Jan J Lerou

Douglas W Bruhnke

Dimitri N Staikos

William T Hicks

The invention relates to a topical formulation in order to deliver an effective amount of broad-spectrum cannabidiol ointment, in conjunction with active ingredients, menthol and camphor. This invention is for the treatment of symptoms and improvement of sensation associated with peripheral neuropathy, particularly of the feet and hands. The present invention also provides for various topical application formulations.

Cannabinoid formulation containing active ingredients and carrier for transdermal absorption to treat neuropathy

A vapor phase process is disclosed for producing HCFC-225s, HCFC-235s, HCFC-226s, HFC-236s, and HFC-227s by reacting certain three-carbon reactants containing at least one less fluorine than, and at least as many hydrogen substituents as the desired product (e.g. propane propylene, allene or methylacetylene) with Cl.sub.2 and HF in the presence of a catalyst consisting essentially of chromium oxide or of chromium oxide which is combined with a refractory oxide, fluorinated and/or modified with manganese, iron, cobalt, nickel, copper and/or zinc. The temperature and contact time for the reaction are chosen to provide a product having the desired fluorine and hydrogen content.

Process for the manufacture of halogen-substituted propanes containing

An organic compound having a cyclic aliphatic moiety is oxidized with a vanadium containing heteropolyanion compound having the formula

Oxidation of organics by a vanadium containing heteropolyanion compound

Cathodic coating for tantalum capacitors containing (a) a mixture of finely divided copper and tin or tin alloy particles dispersed in a solution of (b) organic acid flux, and (c) organic amine in (d) inert organic medium.

Base metal conductor cathode coating for tantalum capacitors

Process for preparing a furan compound by oxidizing a diolefin, using copper as the oxidizing agent, and regenerating spent copper by electrolytic oxidation.

Indirect electrochemical furan synthesis

Separating triarylboranes, e.g., triphenylborane from diaryl substituted boranes, e.g., diphenyl borinic acid by precipitation wherein the triaryl borane is present in a basic solution as the adduct while avoiding coprecipitation of the boranes by neutralizing the solution to a pH not less than the pH defined by the equation

Recovery of triarylboranes

Preparation of triarylboranes, e.g. triphenylborane by reacting an alkali metal, e.g. sodium; an organohalide, e.g. chlorobenzene and an orthoborate ester, e.g. triisopropylorthoborate in an inert organic solvent, recovering the borane by contacting the reaction product with water, removing alcohol from the aqueous mixture and contacting the resultant material with acid to a pH not less than about 6 to form the borane.

Process for the preparation of triarylborane

Preparation of triarylboranes, e.g. triphenylborane by reacting an alkali metal, e.g. sodium; an organohalide, e.g. chlorobenzene and an orthoborate ester, e.g. triisopropylorthoborate in an inert organic solvent, recovering the borane by contacting the reaction product with water while maintaining the ratio of borane to hydrolysis products (e.g. borinic acid) at at least 13/1, distilling volatiles from the aqueous mixture and contacting the resultant material with acid to a pH not less than about 6 to form the borane.

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Hockessin, DE, United States of America

William C Seidel