Philip Morris Inc.

Courtaulds Fibres (holdings) Ltd.

Philip Morris Products Inc.

William B Edwards, Iii

Yoram Houminer

Henry V Secor

John Bryant Paine, Iii

Edward B Sanders

Kenneth F Podraza

Harvey J Grubbs

W Geoffrey Chan

Everett W Southwick

Kenneth A Newman

Jeffrey I Seeman

David L Williams

Charles R Howe

Calvin Roger Woodings

Navin Gautam

Donald E Laslie

John D Naworal

Richard H Cox

Daryl L Faustini

Surnease Drew

Paul N Gauvin

Norman H Cromwell

Filter materials

This invention provides smoking compositions which contain a novel .beta.-hydroxycarboxylate flavorant-release additive. Under cigarette smoking conditions, a combustible filler and/or paper wrapper additive such as calcium bis(2,2-diethyl-3-hydroxy-4-phenylmethylenedecanoate) pyrolyzes and releases .alpha.-hexylcinnamaldehyde as a volatile flavorant component of the cigarette smoke.

Smoking compositions containing an .alpha.-alkylcinnamaldehyde-release

A process for the production of 4,6-dimethyl-7-hydroxynonan-3-one of specific stereochemistry is disclosed. The process results in an active (+)-serricornin.

Novel process for the production of 4,6-dimethyl-7-hydroxynonan-3-one

This invention provides a process for the conversion of an alicyclic .alpha.,.beta.-olefinically unsaturated ketone compound to an acyclic oxocarboxylic acid product which contains at least one less carbon atom per molecule than the ketone starting material. The conversion involves ozonation of the alicyclic .alpha.,.beta.-olefinically unsaturated ketone in an aqueous alcohol reaction medium, followed by a heating step.

Preparation of oxycarboxylic acids

This invention provides a process for the preparation of cotinine and nicotine analogs containing substituents on pyrrolidinone/pyrrolidine ring at the 3' position of cotinine and at the 4' and 5' position of nicotine. The process proceeds via a first step preparation of a cotinine intermediate which is represented by the formula: ##STR1## wherein M is an alkali metal cation.

Nicotine analogs

This invention provides smoking compositions which contain a diacylpiperazine additive such as 1,4-(2-methylpropionyl)-2,3,5,6-tetramethylpiperazine: ##STR1## The preferred diacylpiperazine additives impart enhanced flavor response and smoothness.

1,4-Diacylpiperazine flavored smoking compositions

Optically active nicotine analogs and process for their preparation

Novel azetidine, and particularly 2-pyridyl-azetidine, compounds are disclosed. These compounds are produced from amino-esters by a sequence comprising conversion to the sulfonamide, reduction of the ester to the alcohol, sulfonation of the resultant alcohol and cylization to the N-sulfonylazetidine. This azetidine compound may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.

Azetidine compounds and process for production

Novel azetidine, and particularly 3-pyridyl-azetidine, compounds are disclosed. These compounds are produced from .gamma.-amino alcohols by a sequence comprising disulfonation to produce the sulfonamido-alkylsulfonate and then cyclization to the N-sulfonylazetidine. These azetidine compounds may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.

Growing community of inventors

Richmond, VA, United States of America

William B Edwards, Iii