Quiver Holdings Inc.

William Amar

Christopher Werley

Graham T Dempsey

Yang Lu

Hongkang Zhang

Pin Liu

Arvind Mohan

Nate Bremmer

The inventions provide microscopes for imaging samples within wells of multi-well plates. Microscopes of the disclosure include a beam homogenizer system that shapes a beam from a light source into a shape specific to the bottom of a well of a multi-well plate. In particular, microscopes of the disclosure can illuminate wells for imaging by passing light through a prism that is beneath the sample. The light enters the prism from the side and as refracted into the well at a steep angle such that the light only illuminates about a bottom ten microns of the well. The beam homogenizer shapes the light from the light source so that, instead of hitting the prism as a spot with an irregular shape, the light enters the prism in a substantially rectangular pattern with homogeneous optical power level over the pattern.

Microscope for imaging samples within wells of multi-well plates hold by stage and beam homogenizer for homogenizing beam

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Cambridge, MA, United States of America

William Amar