Steigerwald Arzneimittelwerk Gmbh

Willi Kuper

Wulf Becker

Ulrike Kroll

A method for the production of a plant-based medicament which contains, Menthae piperitae folium, Matricariae flos, Carvi fructus, Melissae folium, Angelicae radix, Liquiritiae radix, Cardui mariae fructus and Chelidonii herba in the form of alcoholic extracts and a medicament produced according to this method, and its use.

Method for the production of a plant-based medicament

In a method for the production of tablets from plant extracts such as St. John's wort extract with an extract content of 80%, the extract treated on a conveyor dryer is compacted after adding 1% of silicon dioxide, and a granulate with a defined particle size distribution and therefore a defined surface area is produced from the compactate. To achieve a high rate of decomposition and active agent release with a low adjuvant content and high extract content, a combination of blasting agents including sodium hydrogencarbonate and two other, lower-dosed blasting agents such as croscarmellose sodium and sodium carboxymethyl starch&#x2014;among other adjuvants&#x2014;is added. The method results in a tablet suitable for oral administration containing 900 mg of St. John's wort extract.

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Gross-Rohrheim, Germany

Willi Kuper