Roche Diabetes Care, Inc.

Karlsruher Institut Fur Technologie

F. Hoffmann-la Roche Ag

Wilhelm Schabel

Georgeta C Lica

Stacy Hunt DuVall

Lukas Wengeler

Philip Scharfer

Philipp Cavadini

Marcel Schmitt

Ralf Diehm

Sibylle Kachel

Stacy Duvall

Georgeta Cami Lica

A device for intermittent coating of a substrate moving in a transport direction relative to the device includes a nozzle body comprising two nozzle jaws; an insertion film having a cut-out provided between the two nozzle jaws, wherein the cut-out in the insertion film forms a nozzle slot within the nozzle body, wherein the nozzle slot extends transversely to the transport direction of the substrate and in parallel with the substrate, and wherein the nozzle slot ends in an outlet gap; and a supply channel, wherein the outlet gap is in flow connection with the supply channel via the nozzle slot. A first of the two nozzle jaws is provided with at least two openings which lead into the nozzle slot in series between the supply channel and the outlet gap and which are closed in a fluid-tight manner toward the nozzle slot by at least two elastically deformable elements.

Method and device for intermittent coating

Reagent matrices and methods are disclosed for improving the stability of test elements with respect to degradation by humidity in the air. The reagent matrices and methods are based upon using an effective amount of a deliquescent material to decrease the sorption of water from the air by other components of a reagent matrix. When the test element is a glucose-specific test strip, and the reagent matrix can include a glucose dehydrogenase enzyme and/or a flavin adenine dinucleotide cofactor, a nitrosoaniline mediator, and a film former, where the deliquescent material may include a salt such as sodium chloride in an amount effective to absorb water from the atmosphere at a rate that is faster than the rate at which the other components of the reagent matrix absorb water from the atmosphere.

Matrix stability compositions, test elements, test systems and methods of use thereof

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Karlsruhe, Germany

Wilhelm Schabel