Doll Gmbh

Dolorgiet Beteiligungs Gmbh

Wilhelm Kunz

Klaus Posselt

Manfred Lohner

Klaus Gruber

The present invention relates to new isopropyl amine compounds and processes for preparing the same. This invention also relates to pharmaceutical compositions containing said isopropyl amine compounds. The new isopropyl amine compounds correspond to the following general formula: ##STR1## wherein R represents a nitrophenyl radical, which may be substituted one or more times by halogen, preferably chloride, and/or by lower straignt- or branched-chain alkyl radicals containing from 1 to 4 carbon atoms an/or by alkoxy radicals containing from 1 to 3 carbon atoms and salts thereof with physiologically compatible acids.

Isopropyl amine compounds

Novel salts of 1,3-bis-(.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropyrimidine (hexetidine) with substituted benzoic acids and processes of preparing these salts are described. These novel salts have useful bacteriostatic activity and show stability in storage. The invention accordingly comprises compositions containing the novel salts and having bacteriostatic activity.

Novel salts of

Novel salts of 1,3-bis-(.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropyrimidine (hexetidine) with substituted benzoic acids and processes of preparing these salts are described. These novel salts have useful bacteriostatic activity and show stability in storage. The invention accordingly comprises compositions containing the novel salts and having bacteriostatic activity. The salts are additionally useful for the purification of hexetidine contained in raw mixtures obtained from the synthesis of this compound.

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Wachtberg-Villiprott, Germany

Wilhelm Kunz