Dr. Madaus & Co.

Wilfried Trost

Rolf Hermann Madaus

Gunter Halbach

New 1-(2',4',6'-trihydroxyphenyl)-propanedione-(1,2)-compounds of the formula ##STR1## wherein R is ##STR2## and their acid addition salts are particularly effective in the treatment of liver diseases.

1-(2,4,6-Trihydroxyphenyl)-propanedione-(1,2)-compounds and therapeutic

Salts of polyhydroxyphenylchromanones, e.g., silymarin or one or more members of the silymarin group, are reacted with a monoaminopolyhydroxy alcohol of the formula ##STR1## wherein X IS AN INTEGER FROM 3 TO 5; AND

Polyhydroxyphenylchromanone salts and therapeutic composition

New, highly effective therapeutic polymers of oligomers of Silybin are provided as well as a process for making same employing organic solvent/mineral acid systems in which Silybin auto-condenses to oligomers thereof having polymerization numbers of, e.g., 2 to 8.

Silybin polymers and therapeutic compositions

Salts of polyhydroxyphenylchromanones, e.g., silymarin or one or more members of the silymarin group, are reacted with a monoaminopolyhydroxy alcohol of the formula ##EQU1## wherein X IS AN INTEGER FROM 3 TO 5; AND

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Bensberg-Frankenforst, Germany

Wilfried Trost