Evonik Degussa Gmbh

Wilfried Bluemke

Thomas Haas

Harald Haeger

Steffen Schaffer

Mirja Wessel

Hans-Georg Joerg Hennemann

Jasmin Gielen

The invention provides a whole cell catalyst which expresses a recombinant &#x3b1;-dioxygenase or the combination of a recombinant fatty acid reductase and a phosphopantetheinyl transferase phosphopantetheinylating the fatty acid reductase, and which in addition to the &#x3b1;-dioxygenase and/or the combination of fatty acid reductase and phosphopantetheinyl transferase expresses a transaminase, characterized in that the phosphopantetheinyl transferase and/or transaminase is preferably recombinant; and a method for the conversion of a fatty acid, &#x3c9;-hydroxy fatty acid, &#x3c9;-oxo fatty acid or a monoester thereof to an amine, comprising oxidation of the fatty acid, &#x3c9;-hydroxy fatty acid, &#x3c9;-oxo fatty acid or the monoester thereof to an oxidation product by contacting with an alkane hydroxylase and/or alcohol dehydrogenase, contacting the oxidation product with a phosphopantetheinylated fatty acid reductase or a &#x3b1;-dioxygenase to give an aldehyde, and contacting the aldehyde with a transaminase.

Growing community of inventors

Schoeneck, Germany

Wilfried Bluemke