Cytokinetics, Inc.

Whitney Walter Smith

Bainian Feng

Gustave Bergnes

John Clifford Chabala

Jeffrey T Finer

David John Morgans, Jr

Xiangping Qian

Pu-Ping Lu

Fady Malik

Erica Anne Kraynack

Kathleen Ann Elias

Adam Lewis Tomasi

Bradley Paul Morgan

Alex R Muci

Todd Tochimoto

Bing Yao

Gustav S Bergnes

Andrew MacDonald

Gustav E Bergnes

David J Morgans

Alex c/o Cytokinetics Inc Muci

Todd c/o Cytokynetics Inc Tochimoto

Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. 

Methods and compositions utilizing quinazolinones

Quinazolinones of formulae 1, 1, 1and 1are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. 

Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. 

Methods and compostions utilizing quinazolinones

Quinazolinone KSP inhibitors

Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

Compositions and methods for treating heart failure

Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

Compounds, compositions and methods

Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, are useful in the treatment of systolic heart failure including congestive heart failure.

Compounds, compositions, and methods

Quinazolinones of formulae 1, 1, 1and 1are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity 

Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity 

Compounds, compositions and methods useful for treating cellular proliferative diseases and disorders, for example, by modulating the activity of KSP, are disclosed.

Quinazolinones of formulae 1, 1, 1and 1are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.

Certain substituted benzamide derivatives of Formula I:selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

Growing community of inventors

El Cerrito, CA, United States of America

Whitney Walter Smith