University of California

The United States of America, As Represented by the Secretary, Department of Health and Human Services

The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc.

USA As Represented by Secretary of the Navy

US Government As Represented by the Secretary of the Army

Wesley M Jackson

Kevin Edward Healy

Eda Isil Altiok

David V Schaffer

Rocky Sung Chi Tuan

Leon J Nesti

Rocky S Tuan

Amit Kumar Jha

The present disclosure provides methods of treating an ocular disease or disorder. The methods involve direct administration into the eye of a conjugate comprising a biologically active polypeptide and a biocompatible polymer.

Methods of treating an ocular disease or disorder

A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle-derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles.

Regenerative tissue grafts and methods of making same

The present disclosure provides methods for sulfonation of hyaluronic acid. The present disclosure provides sulfonated hyaluronic acid, and compositions, including pharmaceutical compositions, comprising the sulfonated hyaluronic acid. The present disclosure provides implantable materials and drug delivery compositions comprising a subject sulfonated hyaluronic acid.

Ethylsulfonated hyaluronic acid biopolymers and methods of use thereof

Tissue graft with non-aligned fiber matrix retains mesenchymal progenitor cells on the non-injury-facing side

Growing community of inventors

Albany, CA, United States of America

Wesley M Jackson