Other

Swiss Analyze Bacteria Ag

Bird-c Gmbh

Bird-c Gmbh & Co Kg

Lubitz, Werner

Werner Lubitz

Wolfgang Jechlinger

Peter Mayrhofer

Dieter Ebert

Mathias Reichl

Margit Sara

Uwe Sleytr

Patrick Sagmeister

Stepanka Resch

Michaela Truppe

Stephanie Resch

Ewald B M Denner

Marek Sramko

Michael Szostak

Beatrix Kuen

Pavol Kudela

Angela Witte

Christian Herwig

Susanne Paukner

Stefan Howorka

Timo Langemann

Gerhard Schroll

Jaroslav Michalek

The invention relates to methods and devices for quantitative determination of bacteria.

Rapid bacteria test

Rapid test for bacteria

The present invention relates to a composition comprising Bacterial Ghosts, optionally an active agent, and a pharmaceutically acceptable carrier and/or excipient for use in the treatment of cancer.

Bacterial ghosts for the treatment of cancer

The invention relates to a fed-batch process for the production of bacterial ghosts based on the decoupling of the lytic gene expression and actual lysis of bacterial cells.

Fed-batch process for the production of bacterial ghosts

The present invention relates to a vaccine comprising dendritic cells and bacterial ghosts for tumor immunotherapy.

Vaccine for tumor immunotherapy

The invention relates to the use of bacterial ghosts (BG) to promote an innate immune response.

Bacterial ghosts for mediating innate immunity

A plasmid is provided comprising the following functional units: a prokaryotic origin of replication, a marker sequence, two specific recombinase recognition sequences and a multiple cloning site, whereby it comprises a gene coding for a sequence specific recombinase, whereby the units are arranged on the plasmid in such a way that the plasmid is divided into a miniplasmid and a minicircle upon expression of the sequence specific recombinase, said miniplasmid comprising the prokaryotic origin of replication, the marker sequence and the gene for the sequence specific recombinase and said minicircle comprising the multiple cloning site.

Minicircle vector production

The invention relates to virus-modified bacteria ghosts and the use thereof, for example, as carrier and targeting vehicles for active ingredients.

Virus-modified bacteria ghosts

The invention relates to bacterial ghost preparation using betapropiolactone for final inactivation of bacteria.

Bacterial ghost (BG) production process using betapropiolactone (BPL) for final inactivation

The invention relates to a method for preparing closed bacterial ghosts by way of specific interactions between partners of a bioaffinity binding pair, and to the bacterial ghosts which can be obtained in this way. Active compounds can be packed into the closed bacterial ghosts. The closed ghosts can be employed in medicine, in the agricultural sphere and in biotechnology.

Sealing closure of bacterial ghosts by means of bioaffinity interactions

The present invention concerns a new epoxypolysaccharide-producing bacterium, the exopolysaccharide isolated from this bacterium and the use of the exopolysaccharide.

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The present invention concerns a method for selecting New Por Poperator sequences from lambdoid phages which have different thermostability compared to the wild-type sequence with regard to binding a repressor. In addition new mutated Por Poperator sequences and their use for the temperature-regulated expression of genes and for production of improved vaccines is disclosed.

Thermostable phage lambda operator mutants for regulating gene expression

The invention relates to a method for preparing closed bacterial ghosts by means of vesicle membrane fusion and to the bacterial ghosts which can be obtained in this way. Active compounds, e.g. genetic material, cell components, pharmaceutical and agricultural active compounds and also markers or dyes can be packaged in the closed bacterial ghosts. Metabolic functions and, where appropriate, the ability of the cells to proliferate can be restored on packaging genetic material in the bacterial ghosts. The closed ghosts can be used in medicine, in the agricultural sphere and in biotechnology.

Closure of bacterial ghost

The invention concerns a process for the recombinant production of S-layer proteins in gram-negative host cells. Furthermore the nucleotide sequence of a new S-layer gene and processes for the production of modified S-layer proteins are disclosed.

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Kritzendorf, Austria

Werner Lubitz