Chinese Academy of Sciences

Tianjin Sinonocy Biological Technology Co., Ltd.

Wenxia Jiang

Qi Liu

Yanhe Ma

Weiya Zhang

Baoliang Mei

Xiaoran Zhang

Disclosed is a solid state biological reaction device, comprising a main tank (), wherein the device further comprises a support () supporting the main tank (), and the support () makes the main tank () be rotational in the horizontal position, and be statically cultured in the vertical position. The device is relatively simple, in particular, the mixing of materials uses the method of a vehicle-tank in combination with rotation, achieving the tank free conversion between the two different poses of vertical and the horizontal; and the device conducts the work of loading, inoculation, cultivation and transplantation and so on in the upright pose, and completes the work of sterilization and mixing of materials and so on in the horizontal pose. The device is not only quick to use and easy to move, but also omits the stirring system which occupies a lot of manufacturing costs, and is easy to use in large-scale production.

Solid state biological reaction device, usage method and use thereof

The present disclosure relates to an improved method for producing ergothioneine, comprising the steps of: (a) inoculatingstrain CGMCC No.6232 into a seed medium, and culturing it to prepare a seed liquor, wherein the seed medium uses soybean cake powder as nitrogen source; and (b) inoculating the seed liquor into a fermentation basal medium, and then culturing it to obtain a fermentation broth ofmycelia. Further, any one or more members selected from NHCl, NHNO, NaCl, polyethylene glycol, folic acid, vitamin B1 (VB1), indolebutyric acid, citric acid, pyruvic acid, arginine, lysine, leucine, aspartic acid, glutamic acid, betaine, histidine, cysteine, methionine, tween, span, chitosan, Fluconazole, Miconazole, Ketoconazole, ethylenediaminetetraacetic acid (EDTA), isopropyl alcohol and dimethyl sulfoxide are added into the fermentation basal medium.

Method for producing ergothioneine by using soybean cake powder as nitrogen source in a seed medium

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Tianjin, China

Wenxia Jiang