Innovent Biologics (suzhou) Co., Ltd.

Nanjing Iaso Biotherapeutics Co., Ltd.

Wenjing Gao

Junjian Liu

Jianfeng Zhou

Yongkun Yang

Guangrong Meng

Yuyu Wang

Guang Hu

Panpan Niu

The invention provides a chimeric antigen receptor (CAR) which can specifically bind to a BCMA protein comprising a BCMA binding structural domain, a transmembrane domain, a costimulatory domain, and an intracellular signaling domain. The invention also provides uses of the CAR in treating diseases or conditions linked to the expression of BCMA.

Chimeric antigen receptor (CAR) binding to BCMA, and uses thereof

The invention provides a chimeric antigen receptor (CAR) which can specifically bind to a BCMA protein comprising a BCMA binding structural domain, a transmembrane domain, a co-stimulatory domain, and an intracellular signaling domain. The invention also provides uses of the CAR in treating diseases or conditions linked to the expression of BCMA.

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Jiangsu, China

Wenjing Gao