University of California

Other

The United States Government As Represented by the Department of Veterans Affairs

Wenhan Chang

Jeffrey A Bluestone

Matthias Hebrok

Qizhi Tang

Alan Dang

Gopika G Nair

Alexis Dang

Casey Ward

Peter Stock

Gaetano Faleo

Eleonora De Klerk

Alfred Li

Thuy Vo

Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.

Preservation of pancreatic islet grafts in the extrahepatic space

Novel articles of manufacture based comprising lattices based on trabecular bone, having a plurality of plates and interconnecting rods. The trabecular bone-inspired lattice may be designed based on the general alignment of plates and rods found in trabecular bone, including anisotropic lattices having one or more predominant axes of mechanical strength. Lumbar fusion implants and other implants are provided having a trabecular bone inspired lattice in which bone graft material may be packed and providing a scaffold for bone fusion and growth. The implants may be based on bone structures having a predominant axis of mechanical strength and may be deployed in sites with the predominant axis of mechanical strength aligned with the primary axis of mechanical stress, such as in the the spine.

Medical implants and other articles of manufacture based on trabecular bone lattices

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San Francisco, CA, United States of America

Wenhan Chang