Merck + Co., Inc.

Wendy S Horn

Jerrold M Liesch

Gerald F Bills

Robert E Schwartz

Francisca Vicente

Deborah L Zink

Janet C Onishi

Fernando Pelaez

Dennis M Schmatz

Robert A Giacobbe

Anne W Dombrowski

Maria T Diez

David L Linemeyer

Isabel Martin

Jack L Smith

E Tracy Jones

Kenneth F Bartizal

Gregory L Helms

Sandra A Morris

Walter Rozdilsky

Myra B Kurtz

Angeles Cabello

Maria S Meinz

Richard K Jansson

Mark Rattray

Isabella Martin

Disclosed is a method for controlling phytopathogenic fungi using pure strains of ATCC 74386 and fungus ATCC 74387. Further, methods of producing a sordarin compound are disclosed. The method includes cultivating each strain separately in a nutrient medium containing assimilable sources of carbon and nitrogen and recovering the compound. A sordarin compound of formula I is also disclosed. Also an antifungal composition containing a sordarin compound is also disclosed.

Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control

There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.

Antifungal agent obtained from hormonema

New antibiotic eicosenoic acids and a method of producing it are described. The acids have been found to have antifungal properties.

Antibiotic eicosenoic acids

This invention relates to compounds of structural formula (I) ##STR1## which are useful as Cholestrol lowering agents.

Cholesterol lowering agents

This invention relates to methods for inhibiting fungal growth employing compounds of formula (I) ##STR1##

Antifungal agents

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Westfield, NJ, United States of America

Wendy S Horn