International Business Machines Corporation

Wendy L Wang

Avijit Chatterjee

Harris M Morgenstern

Greg A Dyck

Danny R Sutherland

A method, system, and computer program product are provided for generating a predictive model. A processor(s) obtains a raw data set (peptide libraries) of patients designated as diagnosed/pre-diagnosed with a condition or not diagnosed with the condition. The processor(s) segments the raw data set into a pre-defined number of groups and separates out a holdout group. The processor(s) performs a principal component analysis on the remaining groups to identify, based on a frequency of features in the remaining groups, common features (principal components) in the remaining groups and weighs the common features based on frequency of occurrence. The processor(s) determines a smallest number of the principal components that yields a pre-defined level of validation accuracy. The processor(s) generates a predictive model, by utilizing the smallest number for a best fit in a logistic regression model. The predictive model provides binary outcomes.

Library screening for cancer probability

In a computing system implementing a virtual memory system having real memory storage frames for storing virtual pages of data and an auxiliary storage system comprising auxiliary storage slots for storing copies of corresponding virtual pages provided in real storage frames, a system and method for freeing auxiliary storage slots to enable further copying of pages thereto. The method comprising the steps of: a) traversing a queue of page frame table entries indicating presence and location of virtual page data in the real storage system; b) determining from the real storage frame backing a page whether the page has been changed in the real storage, and in response, determining whether the page is backed in a corresponding slot in auxiliary storage; c) identifying the auxiliary slot corresponding to the changed frame; and, b) removing the virtual page in said corresponding slot in said auxiliary storage, wherein further room is made available in said auxiliary storage for accommodating storage of other virtual page entries.

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Poughkeepsie, NY, United States of America

Wendy L Wang