Industrial Technology Research Institute

National Taiwan University

Wen-Ting Chiang

Chien-An Chen

Pei-Shin Jiang

Chien-Ting Lin

Cheng-Tai Chen

Jih-Luh Tang

Xuan-Hui Lin

Su-Feng Chiu

Chien-ting Lin

A method for in vitro activation and/or expansion of immune cells is provided, including the steps of: a) providing magnetic particles having multi-protrusive surface modified with at least one type of immuno-inducing substance, in which each magnetic particle includes a copolymer core, a polymer layer, a magnetic substance layer, and a silicon-based layer from the inside to the outside; b) providing a cell solution including at least one type of immune cell in the cell solution; and c) bringing the magnetic particles in contact with the cell solution, in which the at least one type of immuno-inducing substance on the surface of the magnetic particle activates and/or expands the at least one type of immune cell in the cell solution.

Method for in vitro activation and/or expansion of immune cells

Growing community of inventors

Hsinchu County, Taiwan

Wen-Ting Chiang