General Biologicals Corporation

Pacgen Life Science Corporation

Wen-Chi Cheng

Frank Lin

Guan-Yu Lin

Ming-Sun Liu

Chung-Yu Lan

Yao-Peng Xue

Hsueh-Fen Chen

A method for moisturizing skin using P-113 peptide, which comprises administering to the skin of a subject a composition containing a P-113 peptide, wherein the P-113 peptide comprises the sequence of SEQ ID NO: 1. P-113 peptide is hypoallergenic and non-cytotoxic, which means it does not cause harms or allergies to the skin and can be used as an ingredient of cosmetic products. The P-113 peptide fragment has moisture absorption and moisture retention effects, therefore it can be formulated with other ingredients of moisturizing cosmetic products, enhancing the moisturizing effect of other moisturizing ingredients. In addition, the P-113 peptide fragment is capable of inhibiting the production of MMP-9 and thus decreases collagen degradation, thereby achieving the anti-wrinkle and anti-aging effects. The cosmetic disclosed herein comprises not only the peptide, but also active ingredients of cosmetic products and essence liquid formulations.

Method for moisturizing skin using P-113 peptide

A method for treating a microbial infection in a subject includes administering to the subject a pharmaceutical composition which has a therapeutically effective amount of an antimicrobial peptide containing a derivative of P-113.

Method for treating microbial infection

An antimicrobial peptide which is a derivative of the peptide P-113. The amino acid sequence of the antimicrobial peptide is SEQ ID NO: 4 or SEQ ID NO: 5, in which the C-terminus is or is not modified with a NH.

Anti-microbial peptide and method for treating microbial infection

Growing community of inventors

Hsinchu County, Taiwan

Wen-Chi Cheng