Tsinghua University

Kaohsiung Medical University

Kaohsiung Chang Gung Memorial Hospital

Wen-Bin Lee

Gwo-Bin Lee

Chih-Hung Wang

Shiuann-Sheng Lee

Lien-Yu Hung

Chien-Yu Fu

Wen-Hsin Chang

Huey-Ling You

The present disclosure provides an automatic microfluidic system for rapid personalized drug screening including a microfluidic chip. The microfluidic chip includes a fluid storage unit, a fluid driving unit, a reaction unit and a plurality of valve units. The fluid driving unit includes two mixing pumps. Each of the mixing pumps includes two pneumatic micro-pumps, a mixing chamber and a blocking structure. The blocking structure is disposed in the mixing chamber and is connected between the two pneumatic micro-pumps. When the two pneumatic micro-pumps are started alternately, the blocking structure is deflected alone with the operation of the two pneumatic micro-pumps.

Automatic microfluidic system for rapid personalized drug screening and testing method for personalized antibiotic susceptibility

An automatic microfluidic system for antibiotic susceptibility testing of the present disclosure at least includes a microfluidic chip. The microfluidic chip includes a fluid storage unit, a reaction unit, a pneumatic micro-pumping unit and a plurality of valve units. The fluid storage unit is provided for storing a bacterial suspension, a broth and an antibiotic solution. The reaction unit includes a first reaction chamber and at least two second reaction chambers. The pneumatic micro-pumping unit is adjacently disposed to the fluid storage unit and the reaction unit for selectively, repeatedly and quantitatively transporting the broth, the bacterial suspension and the antibiotic solution to the reaction unit to form a first mixing solution and at least two second mixing solutions. The valve units include a plurality of pneumatic micro-valves and a plurality of valve control air holes for controlling the opening and closing of the pneumatic micro-valves.

Automatic microfluidic system for antibiotic susceptibility testing and method of operating thereof

An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5'-ncaaannncnnnnanncnnnnnnnnnnngaannnannngg-3&#x2032;, wherein n is a nucleotide independently selected from 'a,' 't,' &#x201c;c,&#x201d; and &#x201c;g.&#x201d;

Aptamer specific to ovarian cancer and detection method for ovarian cancer

The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.

Oligopeptide specific to ovarian cancer, polynucleotide for encoding oligopeptide, test kit for detecting ovarian cancer and method for detecting ovarian cancer

Growing community of inventors

Hsinchu, Taiwan

Wen-Bin Lee