Wuxi Fortune Pharmaceutical Co., Ltd

Zhuhai United Laboratories Co., Ltd.

Weiwei Mao

Shuhui Chen

Hao Wu

Jian Li

Guoping Hu

Changqing Wei

Xuejian Zheng

Fei Wang

Wenyuan Qian

Lili Fan

Peng Li

Charles Z Ding

Qiang Guo

Yonggang Liao

Liang Fang

Liwei Mu

Yiqiang Huang

The present invention discloses the crystal forms as a JAK inhibitor and their application in the preparation of drugs for the treatment of JAK1 or/and TYK2 related diseases.

Crystalline form of JAK inhibitor and application thereof

Disclosed are a [1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and an application thereof in preparing a drug for treating a disease related to JAK1 or/and TYK2. Specifically, the present invention relates to a compound represented by formula (I), or an isomer or pharmaceutically acceptable salt thereof. (I)

[1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and use thereof

Disclosed in the present application are a class of compounds as JAK inhibitors and use thereof in the preparation of medicaments for treating JAK and TYK2 related diseases. Specifically, a compound represented by formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof is disclosed.

JAK inhibitor and use thereof

The present invention discloses crystal forms and salt forms of a 7H-pyrrolo[2,3-d]pyrimidine compounds and preparation methods thereof, and further discloses use of the crystal forms and the salt forms in the manufacture of a medicament for treating arthritis.

Crystal forms and salt forms of 7h-pyrrolo[2,3-d]pyrimidine compounds and preparation method thereof

The present invention discloses a series of JAK inhibitors, and particularly discloses a compound of formula (I) or a pharmaceutically acceptable salt thereof and the use thereof in preparation of drugs for treating diseases related to JAK. 

JAK inhibitor

A compound having the structure of below Formula (I), or pharmaceutically acceptable salts thereof, are useful as JAK inhibitors, wherein R, R, L, L, T and X are as herein described.

Substituted pyrazoles as JAK inhibitors

A compound having the structure of below Formula(I), or pharmaceutically acceptable salts thereof, are useful as Janus kinase inhibitors, wherein Rand Lare as herein described.

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Shanghai, China

Weiwei Mao