Shanghai Spark Pharmaceutical Co., Ltd.

Weiwei Chen

Kunyuan Song

Gong Chen

Fang Yan

A method for extracting and separating dihydromyricetin from rattan tea, which belongs to the technical field of natural medicine extraction and separation, includes: 1) weighing rattan tea leaves, then adding solvent thereto, stirring and refluxing to extract, filtering, keeping on refluxing extraction of residue, and combining extract; 2) adding activated carbon to the extract, performing decolorization, filtering, retaining the filtrate, and then concentrating the filtrate; and 3) crystallizing the concentrated filtrate, filtering, and washing the crystals with cold water and vacuum drying. The method has simple process, high yield and stability, and is easy to realize industrialized production.

Method for extracting and separating dihydromyricetin from rattan tea

The present disclosure provides a method for preparing diselenide compound. A polar solvent is added to a dihydroflavonol compound, heated to 80&#xb0; C.&#x2dc;100&#xb0; C., kept for 40&#x2dc;50 minutes, then the base in the amount of 0.4&#x2dc;1.0 times the amount of the dihydroflavonol compound is added and reacted at 80&#xb0; C.&#x2dc;100&#xb0; C. for 5&#x2dc;60 minutes, then selenium dioxide in the amount of 0.6&#x2dc;1.2 times the amount of dihydroflavonol compounds at 80&#xb0; C.&#x2dc;100&#xb0; C. The diselenide compound of the dihydroflavonol compound is obtained by reacting at a temperature of 80&#xb0; C.&#x2dc;100&#xb0; C. for 30&#x2dc;150 minutes. The method of the present disclosure has mild reaction, low pollution, does not require an anhydrous and oxygen-free environment, and is suitable for large-scale industrial production.

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Shanghai, China

Weiwei Chen