Beijing Tide Pharmaceutical Co., Ltd.

Weiting Zhong

Hongjun Wang

Yanping Zhao

Liying Zhou

Yuanyuan Jiang

Jing Li

Yanan Liu

Gong Li

Jianmei Pang

Kai Liu

Jing Zhao

Yu Wang

Fajie Li

Yixin He

Weina Liu

The present invention falls within the field of biological medicine, and specifically relates to a method for preventing, alleviating and/or treating fatty liver disease and/or steatohepatitis. The method comprises administering, to an individual in need thereof, an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt, an ester, a stereoisomer, a polymorph, a solvate, an N-oxide, an isotopically labeled compound, a metabolite or a prodrug thereof.

Method for treating fatty liver disease and/or steatohepatitis

A Rho-associated protein kinase (ROCK) inhibitor represented by formula (I), a pharmaceutical composition comprising same, and a use thereof for preventing or treating ROCK-mediated diseases.

Rho-associated protein kinase inhibitor, pharmaceutical composition comprising same, and use thereof

The present invention relates to the field of biomedicine, particularly to double-stranded RNA molecules targeting CKIP-1 and uses thereof, particularly to use of the double-stranded RNA molecules for the treatment of inflammatory diseases such as arthritis, particularly rheumatoid arthritis.

Double-stranded RNA molecule targeting CKIP-1 and use thereof

The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK). 

Rho-associated protein kinase inhibitor, pharmaceutical composition comprising same, and preparation method and use thereof

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Beijing, China

Weiting Zhong