Beijing Team Hospital Management Co., Ltd.

Beijing Tianheng Junwei Pharmaceutical Tech Co., Ltd

Weifeng Yi

Wenbin Yang

Qingwei Jiang

Guimin Zhang

Yongliang Gao

Quanzhi Liu

Junli Zheng

Yuan Di

Changhong Chen

Huangyan Wu

Bo Li

Jianning Sun

Baochuan Liu

Tiejun Zhang

Qiang Zhang

Hongqian Jia

Haisheng Chen

Hua Qin

An osmotic pump controlled release tablet and the preparation method thereof are disclosed. The osmotic pump controlled release tablet is composed of tablet core, semipermeable membrane and optional film coating. The material of said semipermeable membrane is composed of ethyl cellulose and povidone in the ratio of 1:1&#x2dc;1:4 by weight. Said tablet core comprises drug containing layer and push layer. The osmotic pump controlled release tablet also characterizes in that; (1) the angle &#x3b8;formed by the outer curved surface of the drug containing layer and the lateral surface is 120&#xb0;-180&#xb0;; and/or (2) the ratio of Lto r is 0.27-1.0, wherein Lis the vertical distance from the central vertex of the outer curved surface of the drug containing layer to the plane formed by the intersection line between the outer curved surface of the drug containing layer and the lateral surface, and r is the radius of the tablet core.

Osmotic pump controlled release tablet and preparation method thereof

Growing community of inventors

Beijing, China

Weifeng Yi