Decision Sciences International Corporation

Theta Point, LLC

Weidong Luo

Michael James Sossong

Joel Kindem

Chuanyong Bai

Matthew Steiger

Sean Simon

Everett Eugene Van Zuiden

Lorenzo Ramirez Lugo

Nicholas Disher

Methods, systems, and devices are disclosed for charged particle tomography imaging. In one aspect, a system includes a charged particle tomography scanner (CPTS) unit to detect individual charged particles of an emitted charged particle beam delivered to a subject by a charged particle delivery (CPD) system, and a processing unit to determine the angular trajectory change (scattering) and energy loss of the charged particle beam based on detected trajectory information and produce an anatomical image. The CPTS unit includes two detectors, one positioned between the subject and the CPD system, and the other detector positioned opposite to the first detector to detect the trajectory information of the individual charged particles of the charged particle beam having passed through the first detector and the subject, and a motion control unit to move the detectors, in which the detectors' size covers an area at least that of the beam's cross-section.

Charged particle tomography for anatomical imaging

In one aspect, a charged particle tomography and radiation therapy system includes a charged particle tomography scanner (CPTS) unit to detect at least some of the charged particles of an emitted charged particle beam delivered to a region of interest of a subject. A processing unit can determine energy loss of the charged particle beam based on the detected trajectory information. An incoming detector is positioned to detect trajectory information of the at least some of the charged particles entering the subject. An outgoing detector is positioned to detect trajectory information of the at least some of the charged particles passing through and exiting the subject. A motion control unit can control movement of the incoming and outgoing detectors. The incoming and outgoing detectors are sized to cover at least an area substantially equivalent to the beam's cross-section. The processing unit can map radiation dose of the region of interest.

Charged particle tomography scanner for real-time volumetric radiation dose monitoring and control

Disclosed technology can provide a process for generating reconstructed muon image resolution to optimize the use of the limited angular range muon track data collected by a muon tomography system. In one aspect, a process for improving reconstructed muon image resolution for a volume of interest (VOI) imaged by a muon tomography system includes: collecting raw muon track data of cosmic ray muon tracks passing through the VOI; grouping the raw muon track data into two or more subsets of tracks based on at least one angular distribution of the muon tracks in the raw muon track data; generating a set of images of the VOI based on the two or more subsets of tracks; and combining information from the set of reconstructed images and a reconstructed image based on the full set of the raw muon track data to obtain a resulting reconstructed image of the VOI.

Muon tomography imaging improvement using optimized limited angle data

Methods of a high resolution, stationary imaging detector for use in systems for positron emission tomography or single photon emission tomography that uses shadowing effects from intensity attenuation to provide three dimensional positioning information for a source of activity within a field of view of the detector.

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Weidong Luo