Wisconsin Alumni Research Foundation

University of South Florida

Arizona State University

Weibo Cai

Xudong Wang

Jianfeng Cai

Hao Yan

Peng Huang

Chunhai Fan

Youhong Niu

Hyung-jun Im

Lei Kang

Dawei Jiang

Yin Long

Zhilei Ge

Christopher England

Hao Wei

Guang Yao

Hao Hong

A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The electrical energy induces an electric potential across the wound opening producing accelerated skin wound recovery under the voltage fluctuations produced by the power generator.

Electric bandage for accelerated wound recovery

The invention provides an implantable vagal nerve stimulator having a 'passive' generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge without the need for a battery. In this regard, the invention is self-powering and is automatically timed to stomach peristalsis. While sporadic stimulation to the vagal nerve would seem too infrequent to cause weight loss effects, electrical stimulation delivered at the optimal time (e.g., during food consumption) has been found to optimize the effects of vagal nerve stimulation, giving the user's brain a 'full stomach' signal before the user over-consumes food.

Self-powered, auto-responsive implanted vagal nerve stimulator for weight control

Disclosed herein are methods of treating acute kidney injury. The A method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M1 3 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs.

DNA origami nanostructures for treatment of acute kidney injury

Embodiments of the present disclosure provide for RGD mimetic &#x3b3;-AApeptide compounds, &#x3b3;-AApeptide compounds capable of binding an RGD binding site on integrin &#x3b1;&#x3b2;, linear &#x3b3;-AApeptide compounds, cyclic &#x3b3;-AApeptide compounds and multimeric RGD mimetic &#x3b3;-AApeptide compounds, methods of making each, and methods of using each, and the like. In embodiments, the RGD mimetic &#x3b3;-AApeptide compounds can be used in imaging, diagnostics, and treatment of angiogenesis related conditions.

RGD mimetic &#x3b3;-AApeptides and methods of use

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Madison, WI, United States of America

Weibo Cai