Nanjing Tech University

Chongqing University of Arts and Sciences

Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, P.r.c.

Nanjing University of Technology

Nanjing University of Information Science & Technology

Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment of the People's Republic of China

Nanjing Taiwei Technology Co., Ltd.

Wei Zhuang

Hanjie Ying

Chenjie Zhu

Weixin Li

Fei He

Ming Li

Yong Chen

Dong Liu

Qiang Li

Tao Shen

Shoujing Yin

Bo Liu

Yinjing Wan

Ruiming Han

Xiaoyan Tang

Wenjing Li

Changxin Zou

Aiping Liu

Pengpeng Yang

Xiaohan Li

Guoquan Pan

Wenlin Wang

Pingkai Ouyang

Jian Li

Xiaohua Lu

Bin Xu

Zhuhong Yang

Chang Liu

Changsong Wang

Xin Feng

Huanqing Niu

Zhuotao Tan

Zhuang Liu

Yufeng Xie

Jianying Chao

Chenglun Tang

Licheng Li

Hanbei Du

Yudan Zhu

Linghong Lv

Jiannong Shen

Xinjian Xu

Jian Su

Jialin Zhou

Ling Tan

Yaping Fu

Yaoying Han

Weimin Wang

A cordycepin-based derived compound with an anti-tumor effect, and a structure of the compound is as shown in formula I; a cordycepin derivative and a pharmaceutical composition thereof provided by the invention have a good anti-tumor proliferation effect; compared with a parent drug, the cordycepin derivative has better affinity to cell membranes, so that a half-life period of in-vivo metabolism of the drug is longer, and in-vivo remaining time of the drug is longer; compared with other nucleoside anti-tumor drugs, the cordycepin derivative and the pharmaceutical composition thereof provided by the invention have wider types and action ranges of tumors, have excellent inhibition effects on a gastric cancer, a pancreatic cancer, a liver cancer, a small cell lung cancer, a colorectal cancer, melanoma, an ovarian cancer and the like, and have lower side effects and better curative effects.

Cordycepin-based derivatized compound with anti-tumor effect

A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a coenzyme in a solvent to obtain the nitrogen-containing heterocyclic compound and the derivative thereof; compared with the prior art, the method is a green and economical enzymatic-chemical cascade method, and is used for synthesizing nitrogen-containing heterocyclic compounds and derivatives thereof; compared with a common toxic chemical catalyst, the alcohol dehydrogenase is selected as a catalyst in the method, which has the characteristics of high substrate specificity, no pollution, high catalytic efficiency, no toxic solvents and simple post-treatment.

Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzymatic-chemical cascade method

A multi-tag concurrent identification method and a system for a query tree based on feature groups are provided in this disclosure. In the disclosure, a whole data string space is divided into a plurality of disjoint subsets according to features of data strings returned by tags, where each of the subsets contains several different data strings, each of the data strings in the each of the subsets is regarded as a complete tag ID or a partial ID, and the each of the subsets corresponds to a unique query prefix, a length of the prefix is fixed and does not dynamically increase with an actual location of a collision, and when multiple data strings from a same subset return at a same time, a reader is capable of identifying them at a same time in a slot.

Multi-tag concurrent identification method and system for query tree based on feature groups

The invention belongs to the field of rubber tire processing, and particularly discloses an application of a lignin in preparing a radial tire, wherein the lignin is capable of completely or partially replacing resorcinol, and meanwhile, the lignin is also capable of completely or partially replacing an anti-aging agent. Compared with the prior art, the resorcinol is replaced or partially replaced by a biomass-derived lignin or a modified lignin in the invention, so that requirements of cost reduction, environmental protection and no toxicity are satisfied. Especially, the lignin modified by demethylation according to the invention is capable of effectively enhancing various properties of rubber.

Application of lignin in preparing radial tire

A risk prediction and early warning method for water environments based on a water environment model predicting pollution discharge information for all pollution sources in a watershed, and including: selecting pollution sources requiring environmental risk prediction and early warning and dividing these into different risk prediction/early warning levels; determining from official environmental monitoring data and literature research initial elements for environmental pollution risk evaluation; obtaining principal pollution elements affecting pollution events; generating a plurality of environmental risk prediction and early warning models; forming a comprehensive fuzzy risk prediction and early warning model by combining the several risk prediction and early warning models having the best selective performance; inputting principal pollution element values into the comprehensive fuzzy risk prediction and early warning model, and predicting risk values for pollution events at pollution sources. The present method realizes prediction of watershed pollution risk, and resolves present deficiencies in watershed pollution risk prediction and early warning, while improving coverage rates for watershed pollution risk prediction and enhancing the accuracy thereof.

Water environment risk prediction and early warning method

A detection device for simultaneous in-situ measurement of dissolved oxygen at different submerged plant leaf-water interface levels. The detection device includes a dissolved oxygen micro-optrode host. A plurality of detection probes are externally connected to the dissolved oxygen micro-optrode host and can extend out probes. The detection device includes a leaf clamp having an upper clamping head, a lower clamping head, a hinged shaft and a clamping handle. Each of the upper and lower clamping head includes a plurality of water passing cavities penetrating through the back and the front thereof. Each of the upper and lower clamping head includes a plurality of slots horizontally extending inwardly of the corresponding clamping head. The detection device includes a plurality of insertion pieces having a probe groove. The detection probe is locatable in the respective probe groove for fixation. The insertion pieces are insertable and fixable in the slots.

Detection device and method for simultaneous in-situ measurement of dissolved oxygen at different submerged plant leaf-water interface levels

A spliced detection apparatus for simultaneous wide-range in-situ detection of dissolved oxygen in a sludge-water interface of the present invention comprises a dissolved oxygen shimmer host, several detection probes, a casing and detection kits, several vertically through seat chambers being disposed in the casing, the detection kits can be placed and fixed in the seat chambers, the detection kits may be placed on the sludge-water interface, and each detection kit is provided with a vertically through water passage chamber, while the front side face and the back side face of the detection kit are respectively provided with several front slots and rear slots horizontally extending into the detection kit respectively, the detection apparatus further comprises tabs, with probe grooves being provided on the tabs, each detection probe can be put into the probe groove of the corresponding tab and fixed therein, the tabs may be inserted either into the front slots or the rear slots and can enable the probe tips of the detection probes to be placed in the water passage chamber, the detection apparatus can carry out simultaneous wide-range detection of the dissolved oxygen at different heights and horizontal positions of the sludge-water interface, and thus is quick and convenient for use.

Spliced detection apparatus for simultaneous wide-range in-situ detection of dissolved oxygen in sludge-water interface and detection method therefor

A mesoporous composite titanium oxide, which is composed of a mesoporous titanium oxide, the outside surface and the wall of pores of the mesoporous titanium oxide are modified by inorganic matters; inorganic matter contains at least one element selected from carbon, silicon, sulphur, phosphorus and selenium in an amount of 0.01%-25%, on amount of the element mass, of the mass of said mesoporous composite titanium oxide material; at least one mean pore size of pore distribution of the mesoporous compound titanium oxide material is 3-15 nm, the specific surface area is 50-250 m/g, and the pore volume is 0.05-0.4 cm/g. As a catalyst carrier, the rate of conversion of the hydrodesulfurization reaction of the material reaches as high as 98 percent, and as a lithium ion battery cathode material, the specific capacity of the lithium ion battery cathode material reaches as high as 220 mAh/g.

Mesoporous composite titanium oxide and a preparation method

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Nanjing, China

Wei Zhuang