Psilox Ab

Aduro Material Ab

Institut Straumann Ag

Emplicure Ab

Iknow-who Gmbh

Wei Xia

Håkan Engqvist

Susanne Bredenberg

Sigvald Harryson

Cecilia Persson

Le Fu

Bing Cai

The present invention provides a material composition and a process of producing translucent ZrO&#x2014;SiOnanocrystalline glass ceramic (NCGC) with ultra-high flexural strength. The method comprises the following step: (1) prepare homogenous ZrO2-SiO2 nano-sized powder with high purity via a sol-gel method; (2) pressure assisted sintering of ZrO2-SiO2 nano-sized sol-gel powder to obtain translucent ZrO2-SiO2 NCGC. The invention also includes materials manufactured using the method.

Translucent nanocrystalline glass ceramic

The object is the invention is to provide hollow, and preferably porous, spherical CaP particles preferably without the use of strontium ions. This is achieved by a method comprising the steps: a) Providing an aqueous buffer solution of purified water having a pH of 6-10 comprising 20-200 mM sodium ions, 0.1-10 mM potassium ions and 1-10 mM phosphate ions, and wherein the buffer solution is essentially free from strontium; b) adding calcium ions in the range of from 0.1 to less than 2 mM, and magnesium ions in the range of 0.01-5 mM to the buffer solution and forming a mixture; c) heating the mixture of step b) at 60-200&#xb0; C. for at least 5 minutes d) isolating the formed particles; and e) optionally washing the isolated particles using a suitable solvent. The particles comprise 40-70 weight % of calcium, 20-40 weight % of phosphate and 1-25 weight % magnesium. The Ca/P weight ratio is in the range of 1.10 to 1.90 and more than 80 % of the particles have a particle size between 200 to 1500 nm. The particles are essentially free from strontium. A composition comprising the particles may be used for remineralization of teeth or as bone void filling material.

Hollow calcium phosphate particles

A method for formation of spherical particles of ion substituted calcium phosphate. The method is based on precipitation of particles from a buffered solution under static, stirring or hydrothermal conditions. Also, the use of the formed materials and the particles in itself.

Ion substituted calcium phosphate particles

Growing community of inventors

Uppsala, Sweden

Wei Xia