Hong Kong Applied Science and Technology Research Institute Company, Limited

Wei Mong Tsang

Chun Zhang

Yuk Cheung Chan

Jiaqi Wang

Tsz Ho Lau

A derivative spectroscopy system for achieving a tunable resolution of 2 nm or less in resolving spectral components of an input optical signal is provided so as to estimate derivative spectra of the input optical signal based on the resolved spectral components. In the system, a first dispersive-element structure spectrally decomposes the input optical signal into subband signals. A second dispersive-element structure receives part or all of the subband signals and spectrally decomposes the received subband signals to plural spectral components. A material having a temperature-variant refractive index is used to build the second dispersive-element structure, enabling a shift of center wavelength of each spectral component as small as 2 nm of less upon changing a temperature of the second dispersive-element structure. By obtaining three spectral-component sets obtained at three different predetermined temperatures with the center-wavelength shift of 2 nm or less, first- and second-order derivative spectra are obtained with good accuracy.

Methods and apparatus for on-chip derivative spectroscopy

The present invention discloses a non-invasive method of measuring skin thickness and blood glucose concentration of a subject by a Raman system. The advantage of the present invention is that a single Raman spectrum is used to measure both the skin thickness and glucose concentration. The skin thickness and Raman intensity retrieved from the same Raman spectrum are both utilized to yield a more accurate blood glucose concentration. The present invention also discloses a Raman system for measuring physiological data of a subject. It comprises a Raman spectroscopic unit and a signal processing unit.

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Hong Kong, China

Wei Mong Tsang