Danisco A/s

Genencor International, Inc.

Danisco US Inc.

Dupont Nutrition Biosciences Aps

Wei Liu

Andrew Shaw

Karsten Matthias Kragh

Carol Marie Fioresi

Gijsbert Gerritse

Charlotte Refdahl Thoudahl

Casper Tune Berg

Patrick M F Derkx

Huaming Wang

Anja Hemmingsen Kellett-Smith

David Aaron Estell

Scott Douglas Power

Brian Frederick Schmidt

Kirsten Bojsen

Bo Spange Sørensen

Hans De Nobel

Oene Robert Veltman

Edwin Lee

Steve Sungjin Kim

Anja Hemmingen Kellet-Smith

Patrick Maria Franciscus Derkx

Anja Hemmingen Kellett-Smith

Karsten Mathias Kragh

Steven Kim

This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically the amylases of the current invention show an altered exospecifity.

Exo-specific amylase polypeptides, nucleic acids encoding those polypeptides and uses thereof

This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exospecifity.

Variant polypeptides derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the variant polypeptides comprise an amino acid mutation at one or more positions selected from the group consisting of: 121, 161, 223, 146, 157, 158, 198, 229, 303, 306, 309, 316, 353, 26, 70, 145, 188, 272, 339, with reference to the position numbering of aexoamylase sequence shown as SEQ ID NO: 1.

Modified amylases from pseudomonas species, methods of making and uses thereof

This invention relates to nucleic acids encoding amylase polypeptides, the encoded polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exo-specificity and/or thermostability. Some embodiments of the invention relate to said polypeptides and nucleic acids and their uses as non-maltogenic exoamylases in producing food products.

Modified amylases, nucleic acids encoding those amylases and uses thereof

The invention describes a PS4 variant polypeptide derivable from a parent polypeptide having amylase activity selected from the group consisting of: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; with reference to the position numbering of aexoamylase sequence shown as SEQ ID NO: 1, uses of such a polypeptide as a food or feed additive, and nucleic acids encoding such.

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The present invention relates to isolated promoter sequences, particularly a promoter isolated fromdesignated herein as A4-L or A4 and DNA constructs and vectors including the same.

This is invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.

Thermostable amylase polypeptides, nucleic acids encoding those polypeptides and uses thereof

This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.

Described herein are protease inhibitors, variants thereof and methods for their production.

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Palo Alto, CA, United States of America

Wei Liu