Syneurx International (Taiwan) Corp.

Wei-Hua Chang

Guochuan Emil Tsai

Yi-Wen Mao

Han-Yi Hsieh

Tsai-Miao Shih

Jhe Wei Hu

Lu-Ping Lu

ChanHui Huang

A compound of Formula (I): or a pharmaceutically acceptable salt thereof, in which Ring X is a 3 to 7 membered monocyclic ring, at least one of R, R, R, and Ris ORor CHORand the other R, R, R, and Reach independently are halogen, OH, OR, CHOR, COH, OC&#x2550;OR, (C&#x2550;O)R, R, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, H, or absent. Also provided herein are therapeutic uses of the compound of Formula (I).

Compounds and pharmaceutical uses thereof

A method of treating coronavirus infection, comprising administering to a subject in need thereof an effective amount of a composition, wherein the composition comprises one or more compounds of Formula (I): or a pharmaceutically acceptable salt thereof.

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Taipei, Taiwan

Wei-Hua Chang