Atreca, Inc.

Ceres, Inc.

Wayne Volkmuth

Nickolai Alexandrov

Roger I Pennell

Vyacheslav Brover

Richard Schneeberger

Shing Kwok

Nestor Apuya

Jack K Okamuro

Yiwen Fang

Peter Mascia

Tatiana Tatarinova

Edward A Kiegle

Diane K Jofuku

Shaun M Lippow

Daniel Eric Emerling

Jean-Baptiste Dumas

Bill Kimmerly

Ken Feldmann

Yann Chong Tan

Jeff DeFalco

Tito Serafini

Kenneth A Feldmann

Randal Robert Ketchem

William H Robinson

Sean Matthew Carroll

Katherine L Williams

Norm Greenberg

Jessica Finn

Norman Michael Greenberg

Vera Huang

Fengling Liu

Amy Manning-Bog

Alexander Scholz

Nikhil Vad

Jeff Defalco

The present disclosure provides anti-circumsporozoite (CSP) antibodies, compositions comprising such antibodies. Also disclosed are methods of producing the disclosed antibodies and methods of treating or preventing malaria using the same.

Anti-CSP antibodies

Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.

Antibodies that bind tumor tissue for diagnosis and therapy

Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.

Use of nanoexpression to interrogate antibody repertoires

The present invention provides DNA molecules as shown in SEQ ID NO:2199 that constitute fragments of the genome of a plant. The DNA molecules are useful for specifying a gene product in cells as regulatory sequences. One of ordinary skill in the art, having this data, can obtain cloned DNA fragments, synthetic DNA fragments or polypeptides constituting desired sequences by recombinant methodology known in the art or described therein.

Regulatory sequence for plants

The present disclosure provides methods for optimizing barcode design for multiplex DNA sequencing. Also disclosed are DNA barcodes optimized for use with particular sequencing technologies.

DNA barcodes for multiplexed sequencing

The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3' termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait. One of ordinary skill in the art, having this data, can obtain cloned DNA fragments, synthetic DNA fragments or polypeptides constituting desired sequences by recombinant methodology known in the art or described herein.

Promoter, promoter control elements, and combinations, and uses thereof

Growing community of inventors

Foster City, CA, United States of America

Wayne Volkmuth