Other

Genesis Systems LLC

Lap Associates of Nashville Ii

Wayne S Maxson

Joel T Hargrove

Stephen Chakoff

Philip G Meyers

Joe H Delk

The present invention provides a device for immobilizing a cannula or sheath which is inserted into a patient's body in a laparoscopic surgical procedure. The device comprises a cannula skirt through which the cannula passes. The skirt contains a leakage cavity therein which is configured to minimize the pull-off forces which would tend to cause a separation of the skirt from the skin to which it is adhered during the surgical procedure. In addition, the leakage cavity provides enhanced flexibility to the cannula skirt so that the cannula can be angled during the procedure without causing excessive stress on the adhesive. A ratchet ring clamp is also provided on the cannula skirt to constrict the cannula skirt and thereby immobilize the cannula after the cannula has been inserted through the skirt.

Cannula skirt

A pharmaceutical composition suitable for oral administration comprises micronized progesterone in an oil vehicle which is high in glycerides of polyunsaturated fatty acids. Micronized progesterone particles suspended in such an oil vehicle are absorbed more readily into the bloodstream and achieve high progesterone blood serum levels. The pharmaceutical composition according to the invention can be readily formulated into capsules and administered for the treatment of premenstrual syndrome.

Method and dosage form for treatment of premenstrual syndrome

The present invention provides a device for immobilizing a cannula or sheath which is inserted into a patient's body in a laparoscopic surgical procedure. The device comprises a cannula skirt through which the cannula passes. The skirt contains a leakage cavity therein which is configured to minimize the pull-off forces which would tend to cause a separation of the skirt from the skin to which it is adhered during the surgical procedure. In addition, the leakage cavity provides enhanced flexibility to the cannula skirt so that the cannula can be angled during the procedure without causing excessive stress on the adhesive.

Method for treatment of premenstrual syndrome

A pharmaceutical composition is provided for oral administration. The composition comprises estradiol dissolved in an oil vehicle containing a suspension of micronized progesterone. The oil vehicle is high in glycerides of polyunsaturated fatty acids. The estradiol and micronized progesterone contained in the oil are more readily absorbable in the blood stream and achieve enhanced estradiol and progesterone blood serum levels. The pharmaceutical composition according to the invention can be readily formulated into capsules and administered for the treatment of menopausal symptoms.

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Nashville, TN, United States of America

Wayne S Maxson