Esa, Inc.

Ixcela, Inc.

Environmental Sciences Associates, Inc.

Esa Biosciences, Inc.

Other

Duke University

Mayo Foundation for Medical Education and Research

Dionex Corporation

Environmental Sciences, Inc.

Wayne R Matson

Samantha A Matson

Erika N Ebbel-Angle

Srikant Sarangi

Ronald Vitukevich

Richard M Weinshilboum

Rima Kaddurah-Daouk

Bruce S Kristal

Liewei Wang

Michiaki Kubo

Taisei Mushiroda

Balmiki Ray

Joanna Biernacka

Paul E Milbury

Mark Frye

Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's health based on the metabolite levels measured.

Detection and modification of gut microbial population

Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.

Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.

Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.

Modulating the aryl hydrocarbon receptor system to treat major depressive disorder

Provided is a method for reducing a potential for neurological damage of an animal at risk of head injury, by administering to the animal before exposure to the risk indole-3-propionic acid, indole lactic acid, or a salt, ester or protein complex or marginally bound preparation thereof, or a mixture thereof, in a suitable carrier.

IPA as a protective agent

Indole-3-propionic acid as a marker and for treatment for Huntington Disease.

IPA as a therapeutic agent, as a protective agent, and as a biomarker of disease risk

Indole lactic acid or a mixture of indole lactic acid and indole-3-propionic acid for treatment of Huntington's disease

IPA as a therapeutic agent and a biomarker for disease risk for Huntington's disease

The health condition of a living organism is detected by electrochemically analyzing samples from selected areas of the body of said living organism for elevated free levels of nucleotide excision products resulting from DNA or RNA damage.

Detection of DNA damage

A sample pre-separation and concentration system for detecting low levels of analytes in highly complex mixtures includes a plurality of trapping columns having a high selectivity for classes of compounds of interest, upstream of a standard separation column. The system may be used, for example, to measure urinary 8 hydroxy 2&prime; deoxyguanoisine.

Electrochemical analysis system

A method of pre-treating carbon or graphite material to increase porosity and render pore size more uniform includes etching by electrochemically pulsing the material in an acid saline solution and optionally steam treating.

Growing community of inventors

Ayer, MA, United States of America

Wayne R Matson