Direvo Industrial Biotechnology Gmbh

Molecular Logix, Inc.

Bayer Healthcare LLC

Crispr Therapeutics Ag

Wayne M Coco

Birgitta Leuthner

Oliver Kensch

Ulrich Kettling

Ulrich Haupts

Andreas Scheidig

Nadine Koch

A Katrina Loomis

Moritz Schmidt

Ute Beister

Markus Rarbach

Philip P Pienkos

Christina Galonska

Andre Cohen

The present invention provides an insertion, deletion and/or substitution mutein of wild-type&#x3b2;-mannanase having enhanced thermostability, proteolytic stability, specific activity and/or stability at low pH, a nucleic acid molecule encoding said mannanase mutein, a composition comprising said mannanase mutein; a method for its preparation, and its use for food and feed processing, for coffee extraction and the processing of coffee waste, as a supplement to food and feed, for enzyme aided bleaching of paper pulps, as bleaching and/or desizing agent in textile industry, for oil and gas well stimulation by hydraulic fracturing, as detergent, for removal of biofilms and in delivery systems, or for the processing of renewable resources intended for the production of biological fuels.

Mannanases

The present invention features polypeptides that have at least 90% amino acid identity to wild-type epidermal growth factor, and also have epidermal growth factor biological activity that is greater than the biological activity of wild-type epidermal growth factor.

Epidermal growth factor agonists

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Cologne, Germany

Wayne M Coco