Other

Novartis Ag

Novartis Corporation

Eyesense Ag

Wayne Front March

Mary Flowers Mowery-McKee

An apparatus for measuring ocular and/or blood glucose levels comprises

Apparatus for measuring blood glucose concentrations

An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety which is displaced from the receptor moiety by the analyte is measured and provides a means of determining analyte concentration in an ocular fluid, such as tears, aqueous humor, or interstitial fluid. The concentration of the analyte in the ocular fluid, in turn, indicates the concentration of the analyte in a fluid or tissue sample of the body, such as blood or intracellular fluid.

Ocular analyte sensor

An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety which is displaced from the receptor moiety by the analyte is measured and provides a means of determining analyte concentration in an ocular fluid, such as tears, aqueous humor, or interstitial fluid. The concentration of the analyte in the ocular fluid, in turn, inidicates the concentration of the analyte in a fluid or tissue sample of the body, such as blood or intracellular fluid.

A unique glucose sensor to determine the glucose level in patients, for example, for use in treating or diagnosing diabetes. The patient's eye is automatically scanned using a dual source of polarized radiation, each transmitting at a different wavelength at one side of the cornea of the patient. A sensor located at the other side of the cornea detects the optical rotation of the radiation that passed through the cornea. The level of glucose in the bloodstream of the patient is a function of the amount of the optical rotation of the radiation detected at the other side of the cornea of the patient. The result is transmitted to a remote receiver that is coupled to a readout device to thereby provide non-invasive glucose determinations of high specificity and reliability.

Non-invasive glucose sensor system

A unique glucose sensor to determine the glucose level in patients, for example, for use in treating or diagnosing diabetes. The patient's eye is automatically scanned using a source of radiation at one side of the patient's cornea. A sensor located at the other side of the cornea detects the radiation that passed through the cornea. The level of glucose in the bloodstream of the patient is a function of the amount of radiation detected at the other side of the cornea of the patient. The result is transmitted to a remote receiver that is coupled to a readout device to thereby provide non-invasive glucose determinations.

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Galveston, TX, United States of America

Wayne Front March