Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Abbott Laboratories Corporation

Les Solutions Medicales Soundbite Inc.

Avdanced Cardiovascular Systems, Inc.

Wayne E Cornish

Mark Richardson

Marc Mehrzad Jalisi

David M Anderson

Douglas H Gesswein

Robert C Esselstein

David H Burkett

John Schreiner

Lawrence E Brennan

Ryan Grandfield

Olin J Palmer

James M Jacobs

Emmanuel C Biagtan

Kent C Stalker

John Arthur Simpson

Peter J D'Aquanni

Pablito Buan

David K Wrolstad

Sepehr Fariabi

Nancy A Nicotra

John E Papp

Daryush Mirzaee

William Joseph Boyle

Benjamin C Huter

Scott Jason Huter

Frank E Manning

Philip S Yip

Mo Jafari

Jonathan M Howland

Aaron Baldwin

Sharon Wong

Raleigh A Purtzer

Kathern J Lind

Robert C Hazelden

Michael Plattner

Thomas Tokarchik, Iii

Kent C B Stalker

John Francis Boylan

W Stan Wilson

Brandon Gosiengfiao

John J Nelson, Iii

Travis Richard Yribarren

Robert James Siegel

Henry Nita

Martin Brouillette

Louis-Philippe Riel

Steven Dion

Leonard Darius Barbod

Edwin P Mahieu

Carl P Frick

Robert J Peralta

Michelle E Alexander

Arthur R Tyre

Manuel Charlebois-Menard

James M Jacob

Kevin Britton

Arno Wagner

Martinos Tran

Shruti Bajaj

Jessica M Saenz

Mark T Richardson

Ryan c/o Advanced Cardiovascular Systems Inc Grandfield

Marc M c/o Sara Beeter Jalisi

Kent Cb Stalker

Vincent P Bavaro

Lawrence Brennan

A device for transmitting mechanical waves, including a mechanical waveguide having an elongated shape and extending between a proximal end and a distal end for propagating the mechanical waves coupled at the proximal end up to the distal end, and a radiopaque marker secured to the mechanical waveguide adjacent to the distal end thereof.

Mechanical waveguide provided with a marker thereon

A guide wire for use in a medical procedure having a shapeable tip integral with and made from the distal end of a superelastic nitinol distal section of the guide wire, wherein the shapeable tip can be finger kinked. Such a guide wire includes an elongated core made from a superelastic nitinol alloy at the distal end, the distal end of the elongated core having a tapered section leading to a shapeable distal tip. The shapeable tip is an extension of the distal end of the nitinol distal section, and includes permanent strain hardening from at least two different radial directions imparting crystallographic texture in the radial directions that eliminate superelasticity so that permanent deformation can be achieved with finger pressure.

Nickel&#x2014;titanium core guide wire

An intravascular guide wire having two core materials joined together without the use of a connector tube or sleeve, the core materials being stainless steel and psuedoelastic metal alloy, nitinol. The core materials are joined to each other through an intermediate transition piece made essentially of nickel, which is welded on either side to the two core materials. In a multi-segment intravascular guide wire, discrete, high modulus and medium modulus core portions of different materials are welded to a shapeable, low modulus distal core portion made of a third material having a flattened, shapeable section at a most distal end that is not welded to but made from the distal core portion, so the flattened, shapeable section can be deformed to create a steerable tip. Processes such as simultaneous resistance and friction welding can be used to join the core portions.

Guide wire with core having welded wire segments

The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

Guidewire having linear change in stiffness

Nickel-titanium core guide wire

A guide wire for advancing a medical device such as a catheter through a patient's body lumen which has an elongated core with proximal and distal core section, a flexible tubular member such as a coil on the distal end. The wire core includes surface textures that are translated into the overlying coating. Alternatively, the coating has its own surface texture. The surface textures include randomly or non-randomly spaced bumps, divots, ridges, helical grooves, longitudinal grooves, undulations, etc.

Textured polymer coated guide wire and method of manufacture

There is disclosed medical devices, such as stents, guidewires and embolic filters, comprising a binary alloy of titanium and one binary element selected from platinum, palladium, rhodium, and gold. There is also disclosed a radiopaque marker comprising the disclosed binary alloy, as well as medical devices having the radiopaque marker attached thereto. Methods of attaching the radiopaque marker to the medical devices, such as by welding, are also disclosure also disclosed.

Radiopaque markers and medical devices comprising binary alloys of titanium

A color coding is applied to medical guide wires by coloring portions of the guide wire to distinguish similar guide wires and guide wire portions from a particular manufacturer. The metallic elongate core can be colored using various methods such as electrochemical processes, sputtering, electroplating, and laser inducing microstructures to alter the surface characteristics of the elongate metallic core. Alternatively, the outer layer of the guide wire can be color coded by using non-standard colors or by introducing a colored band on the guide wire.

Color coded guide wire and methods of making same

A guide wire includes an elongate core section and a flexible member disposed on the distal end, the flexible member including a first wire wound into an inner helical coil in a first direction and a second wire wound into an outer helical coil wrapped about the first helical coil in the opposite direction. The two combined helical coils add stiffness and torque transmission to the guide wire without sacrificing tactile feedback.

Guide wire with soldered multilayer coil member

A locking component for locking a medical device onto a guide wire. Such medical devices include, for example, an embolic filter assembly used to capture embolic material that may be created and released into a patient's vasculature during a stenting or angioplasty procedure. The embolic filter assembly tracks along the guide wire, and is delivered to a treatment site where it is locked in place and deployed. The locking component enables the filter assembly to lock onto any standard guide wire, and does not require a modified guide wire that has a specially-designed fitting or stop to accomplish the locking function.

Locking component for an embolic filter assembly

A guide wire for guiding a medical device within a patient is disclosed. The guide wire has a solid inner core made of high modulus material such as Conichrome&#xae; or a rhenium alloy, and an outer shell made of a flexible, kink resistant material such as a nickel-titanium alloy. Preferably, the modulus of elasticity of the inner core material is at least about 20 percent greater than that of the outer shell material. The outer shell is mechanically joined to the inner core through a drawing or cladding process. In various embodiments, the distal end of the guide wire can be tapered by grinding away the outer shell to expose the inner core. Because of its stiffness, it can be manually shaped by the physician or cardiologist.

Metal composite guide wire

The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone.

Composite guidewire withdrawn and filled tube construction

Growing community of inventors

Oceanside, CA, United States of America

Wayne E Cornish