Medtronic Minimed, Inc.

Pacesetter, Inc.

Siemens-pacesetter, Inc.

Wayne A Morgan

Rajiv Shah

David Choy

Peter G Schultz

Udo Hoss

Gopikrishnan Soundararajan

James L Henke

Bahar Reghabi

Varaz Shahmirian

Barry Keenan

Lu Wang

Ronald J Lebel

Cary D Talbot

Timothy J Starkweather

Michael E Miller

John Joseph Mastrototaro

Rebecca K Gottlieb

John Charles Gord

Ning Yang

Bradley Chi Liang

Raghavendhar Gautham

Jenn-Hann Larry Wang

Richard E Purvis

Sam W Bowman, Iv

John C Mueller, Jr

Sheldon B Moberg

Gabriel A Mouchawar

Paul Milton Meadows

Brian M Mann

James D Causey, Iii

Colin A Chong

Robert C Mucic

Sergiu Silvian

Peter Carl Lord

Jay A Yonemoto

Daniel H Villegas

Philip T Weiss

Ali Enayat Zadeh

Yiwen Li

David Y Choy

Peter Schultz

John C Mueller

Edward Chernoff

Phillip B Hess

Catherine M Szyman

Philip B Hess

Manjunath Sirigiri

Genival D De Barros

Carlos A Callirgos

Joseph Paul Brinson

Arthur A Campbell

Glenn O Spital

Curtis A Knight

Mae-Mae Shieh

David Yueh-Hua Choy

Tom W Richards

Sam W Iv Bowman

Paris Chen

The double layer capacitance of a working electrode of a sensor may be measured with minimal disruption to the sensor equilibrium by open circuiting the working electrode and measuring the voltage drift on a periodic, or as-needed, basis. The values of the double layer capacitance may be monitored over time to determine, e.g., sensor age and condition.

Methods, systems, and devices for electrode capacitance calculation and application

A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

Method of and system for stabilization of sensors

A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

Methods and systems for detecting the hydration of sensors

A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is used to open the self-calibration module circuit and either measure the IR drop using a high-frequency (MHz) ADC module, or estimate it through linear regression of acquired samples of the voltage across the sensor's working and reference electrodes (Vmeasured) over time. The IR drop is then subtracted from the closed-circuit value of Vmeasured to calculate the overpotential that exists in the cell (Vimportant). Vimportant may be further optimized by subtracting the value of the open-circuit voltage (Voc) across the sensor's working and reference electrodes. The values of Vmeasured and Vimportant are then controlled by respective first and second control units to compensate for the IR drop.

Real-time self-calibrating sensor system and method

A relay device transfers information between a sensor system, which measures a physiological characteristic level of a user, and a fluid delivery system, which infuses a fluid into a user. The relay device includes a sensor system receiver for receiving communications from the sensor system in a sensor system format. The relay device also includes a processor for processing the communications from the sensor system and converting the communications for transmission in a delivery system format. The relay device further includes a delivery system transmitter for transmitting the converted communications in the delivery system format to the fluid delivery system. The sensor system and delivery system formats may utilize different frequencies and/or different communication protocols for communications transmitted between the sensor system and the fluid delivery system through the relay device.

Relay device for transferring information between a sensor system and a fluid delivery system

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Northridge, CA, United States of America

Wayne A Morgan