Thermo Electron Corporation

Thermedics Inc.

Tmca Foundation Inc.

Warren C Clay

Victor L Poirier

Benedict D Daly

Disclosed is a percutaneous access device (PAD) for long-term skin penetration and use as an access port in the body of a patient. The buttonlike device includes a flat skirt for subdermal anchoring of the PAD and a neck through which a tube may extend for transmission of materials to or from the body. A two-stage porous bed covering the skirt and at least a portion of the neck promotes formation of a tight, infection-free barrier between the percutaneous access device and adjacent tissues, stabilizing the device for long-term use. The first stage of the bed retards downgrowth of epidermal cells for a time sufficient for mature collagen to form in the second stage, thereby permitting the tight dermal/biomaterial interface or barrier to form at a location near the junction of the two stages.

Percutaneous access device

A pneumatic pump adapted primarily as a left ventricular heart assist device includes a flexible bladder with a rigid housing. A pneumatic driver applies rhymical pulses between the bladder and the housing to repetitively collapse the bladder and establish a pumping action through the bladder, in conjunction with check valves in the inlet and outlet to the bladder. Between the driver and the pump there is provided a pneumatic pulse limiter which includes a flexible diaphragm isolating the driver from the pump. Pulses from the driver are transmitted to the pump only through the flexible diaphragm and the diaphragm is constrained to move only within established limits. Regardless of the magnitude of the pulse from the driver, the maximum pulse applied to the pump cannot exceed that corresponding to the maximum displacement of the diaphragm. Between successive pulses, the portion of the system between the driver and the flexible diaphragm is depressurized. The rapidity with which depressurization occurs is enhanced by provision of a quick release valve between the driver and the diaphragm.

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Lynn, MA, United States of America

Warren C Clay