Cardiac Pacemakers, Inc.

Cyberonics, Inc.

Livanova Usa, Inc.

Wangcai Liao

Bin Mi

Jeffrey E Stahmann

Keith R Maile

Paul J Huelskamp

Yunlong Zhang

Eyal Doron

Binh C Tran

Jicong Zhang

Rodney W Salo

Avi Penner

Abraham Penner

A system includes one or more memory devices having instructions stored thereon that, when executed by one or more processors, cause the one or more processors to perform operations including calculating a depression detection value based in part on a first depression-indicative value based on a first body parameter value, a second depression-indicative value based on a second body parameter value, and a weighting applied to at least one of the first depression-indicative value and the second depression-indicative value, comparing the depression detection value to a first threshold and a second threshold that is different from the first threshold to detect an onset of a depression episode, and initiating neurostimulation therapy by one or more electrodes responsive to detecting the onset of the depression episode.

Methods and systems to diagnose depression

A method includes receiving sensor data at a processor from sensors of an external medical device. The sensor data corresponds to at least a first body parameter value for a patient and a second body parameter value for the patient. The method includes determining a first depression-indicative value based on the first body parameter value, a second depression-indicative value based on the second body parameter value, a depression detection value as a function of a first weight applied to the first depression-indicative value and a second weight applied to the second depression-indicative value, and a depression state based at least in part on a comparison of the depression detection value to one or more threshold values.

Systems and methods provide for ambulatorily sensing pulmonary artery pressure from within a patient, and producing a pulmonary artery pressure measurement from the sensed pulmonary artery pressure. Power is ambulatorily provided within the patient to facilitate sensing of the pulmonary artery pressure and producing of the pulmonary artery pressure measurement. Acute pulmonary embolism is detected based on a change or rate of change in the pulmonary artery pressure measurement. An alert is preferably generated in response to detecting pulmonary embolism.

System and method for detection of pulmonary embolism

Methods and systems for characterizing a seizure event in a patient, including determining a time of beat sequence of the patient's heart, determining a first HR measure for a first window, determining a second HR measure for a second window, wherein at least a portion of the first window occurs after the second window, determining at least one HR parameter based upon said first HR measure and said second HR measure, identifying an onset of the seizure event in response to determining that at least one HR parameter crosses an onset threshold, identifying an end of the seizure event in response to determining that at least one HR parameter crosses an offset threshold.

Identifying seizures using heart data from two or more windows

Methods, systems, and apparatus for recharging medical devices implanted within the body are disclosed. An illustrative rechargeable system includes a charging device that includes an elongate shaft having a proximal section and a distal section. The distal section is configured to be delivered to a location within the body adjacent to the implanted medical device. The charging device includes a charging element configured to transmit charging energy to a receiver of the implanted medical device.

Methods and systems for recharging an implanted device by delivering a section of a charging device adjacent the implanted device within a body

Methods and systems for adjusting neighborhood widths of candidate heart beats, including being provided with a plurality of candidate heart beats, the candidate heart beats being associated with neighborhood widths in the time domain, and scaling the neighborhood widths, an amount of scaling being determined according to one or more previous heart rate statistics.

Adjusting neighborhood widths of candidate heart beats according to previous heart beat statistics

Methods and systems for detecting a seizure event, including receiving heart beat data versus time for a patient, detecting an increase in the heart rate of a patient from a baseline heart rate to an elevated heart rate, detecting a decrease in heart rate from the elevated heart rate, for a time interval occurring during said decrease in heart rate, determining at least one of a) a rate of decrease in heart rate and b) a rate of change in a rate of decrease in heart rate, and detecting a seizure event in response to determining at least one of a) a rate of decrease in heart rate greater than a threshold rate of decrease, and b) a rate of change in the rate of decrease less than a threshold rate of change in a rate of decrease.

Identifying seizures using heart rate decrease

Methods, systems, and apparatus for recharging medical devices implanted within the body are disclosed. An illustrative method of recharging an implanted medical device includes delivering a charging device to a location adjacent to the implanted medical device, activating a charging element coupled to the charging device and transmitting charging energy to a receiver of the implanted medical device, and charging the implanted medical device using the transmitted charging energy from the charging device.

A system and a method of disposing a second sensor module overlying a first sensor module system is described. A first assembly including an expandable anchor and a sensor module is at least partially overlapped by a second assembly including an expandable anchor and a sensor module. If necessary or desired, the functions of the second sensor module can replace the functions of the first sensor module. The sensor module may include a blood pressure sensor.

Growing community of inventors

Houston, TX, United States of America

Wangcai Liao