Brainsonix Corporation

Methode Electronics, Incorporated

Walter William Wurster

Michael Allen Gustafson

Mark Evan Schafer

Shelly Jordan

Elaine Patrice Pelletier

Alex Korb

Richard Alan Waltz

Gregory Thomas Mark

Russell G Larsen

Andrew Wallace

Hannah Han

Andrew M Wallace

Russel G Larsen

Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.

Treating degenerative dementia with low intensity focused ultrasound pulsation (LIFUP) device

A stereotactic frame includes a vertical column that extends up from a base. A first laterally extending support arm extends from a first side of the column and a second laterally extending support arm extends from a second side of the column. One of the first or second support arms may include a transducer assembly. The transducer assembly may move a focal point of the transducer in different lateral and longitudinal horizontal positions and different vertical positions. The transducer assembly also may move the focal point of the transducer beam into different pivoting angled positions. The stereotactic frame applies repeatable ultrasonic energy to targets inside a patient without using invasive attachment procedures and without having to repeatedly use expensive magnetic resonance imaging (MRI) machines.

Stereotactic frame

A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.

Focused ultrasonic transducer navigation system

An electrical connector includes a first and second array of flexible beams that are overlapped within a hood and that define a substantially cylindrically cavity for receiving a mating connector. Contact areas of each of the flexible beams may be shaped to define multiple contact points, thus increasing the overall area available for current to pass.

Stamped beam connector

Growing community of inventors

Reno, NV, United States of America

Walter William Wurster