The Wistar Institute

Walter U Gerhard

Laszlo Otvos

Carlo M Croce

Hilary Koprowski

Laslo Otvos

The present invention provides multiple antigenic agents compositions and the use thereof to prevent or treat viral infections.

Composition and method for preventing or treating a virus infection

The present invention provides multiple antigenic agents compositions and the use thereof to prevent or treat viral infections. The multiple antigenic agents of the invention contain at least one of a B cell determinant, a T cell determinant, or a targeting molecule attached to a core peptide composed of Lys-Gly repeats.

Multiple antigenic agents and methods for using the same

Continuous cell lines of genetically stable fused cell hybrids capable of producing large amounts of monoclonal antibodies against specific viruses and their antigenic determinants have been developed. The cell lines are fused cell hybrids between viral antibody producing cells and myeloma cells. Fused cell hybrids between influenza virus-primed mouse spleen cells and mouse myeloma cells can be maintained indefinitely in culture and continue to produce large amounts of anti-influenza antibody.

Growing community of inventors

Philadelphia, PA, United States of America

Walter U Gerhard