Covidien LP

Sofradim Production

United States Surgical Corporation

Tyco Healthcare Group LP

Walter Skalla

Steven L Bennett

Nathaniel Mast

Kevin Lavigne

Joshua Benjamin Stopek

Timothy Sargeant

Saumya Banerjee

Ahmad Robert Hadba

Nadya Belcheva

Seth Gleiman

Jonathan D Thomas

Thierry Brune

Robert Vestberg

Ying Jiang

Danyel Racenet

Darlene Nebinger

Arpan Desai

Allison Calabrese

Lauren Vernlund

Steven Bennett

Nathanial Mast

Allison Foss

A biodegradable triblock copolymer comprising: an A-B-A' structure wherein the A and A′ blocks each include polylactide, the B block includes from about 55 to about 100 mole percent of polytrimethylene carbonate and 0 to about 45 mole percent polylactide, and the biodegradable triblock copolymer overall includes from about 15 to about 25 mole percent of the polytrimethylene carbonate and from about 75 to about 85 mole percent of the polylactide. Also provided are compositions and implantable medical devices made therefrom.

Biodegradable triblock copolymers and implantable medical devices made therefrom

A biodegradable triblock copolymer comprising: an A-B-A' structure wherein the A and A&#x2032; blocks each include polylactide, the B block includes from about 55 to about 100 mole percent of polytrimethylene carbonate and 0 to about 45 mole percent polylactide, and the biodegradable triblock copolymer overall includes from about 15 to about 25 mole percent of the polytrimethylene carbonate and from about 75 to about 85 mole percent of the polylactide. Also provided are compositions and implantable medical devices made therefrom.

The present disclosure relates to a medical device and methods of using the same. In embodiments, the medical device may be a buttress formed of nucleophilic buttress components and electrophilic buttress components which react to both form the buttress and provide the buttress with self-sealing capabilities after a staple or some other fixation device is placed therethrough, thereby enhancing its hemostatic properties. In other embodiments, the medical device is a hernia patch formed of a fibrous substrate, nucleophilic precursor components and electrophilic precursor components.

Medical devices with sealing properties

The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.

Hydrogel implants with varying degrees of crosslinking

Methods for producing biocompatible compositions are provided. The biocompatible compositions include an aliphatic polyester macromer produced without the use of solvents or catalysts. The resulting aliphatic polyester macromer may be reacted with a polyisocyanate to form an end-capped aliphatic polyester macromer which, in turn, may be reacted with a polyol to produce a polyurethane. The polyurethane, in turn, may be reacted with a second polyisocyanate to produce an isocyanate-functional polyurethane. The compositions prepared by the methods of the present disclosure may be used as adhesives or sealants for medical/surgical uses.

Biodegradable macromers

Growing community of inventors

Old Lyme, CT, United States of America

Walter Skalla