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Agere Systems Optoelectronics Guardian Corp.

Danielle's Buddy, Inc.

Electrikus, Inc.

Walter Jeffrey Shakespeare

Matthew J Schurman

Phillip William Wallace

William Henry Bennett

Howard P Apple

Brian H Moore

Viet Hoang

George Edward Kechter

Jason T Iceman

Samuel Reichgott

Seyed Ehsan Jalilian

Ajay Sandhu

Dongliang Huang

Chris Henrikson

Adrian Dumitru

Thomas Clement

Richard Bendicks Bylsma

Dominic Paul Rinaudo

Thomas Edward Sedlack

Tom Clement

Clarence William Crompton

Gustav Edward Derkits, Jr

David Gerald Coult

Carl Edward Gaebe

Rory Keene Schlenker

Frederick Arthur Yeagle

Rudolph Conrad Schweizer

Duane Donald Wendling

Christopher Eugene Young

Parker Egan Jones

William Henry Bennet

Lawrence P Levitt

Sharone Vaknin

Lacrosse accessory

There is described a method for interrogating optical fiber comprising fiber Bragg gratings ('FBGs'), using an optical fiber interrogator. The method comprises (a) generating an initial light pulse from phase coherent light emitted from a light source, wherein the initial light pulse is generated by modulating the intensity of the light; (b) splitting the initial light pulse into a pair of light pulses; (c) causing one of the light pulses to be delayed relative to the other of the light pulses; (d) transmitting the light pulses along the optical fiber; (e) receiving reflections of the light pulses off the FBGs; and (f) determining whether an optical path length between the FBGs has changed from an interference pattern resulting from the reflections of the light pulses.

Optical interrogator for performing interferometry using fiber Bragg gratings

Ride-in toy boat with runners

Optical coherence tomography (herein 'OCT') based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.

Multispot monitoring for use in optical coherence tomography

Flowometry in optical coherence tomography for analyte level estimation

The present invention relates to a method and system for estimating blood analyte levels using a noninvasive optical coherence tomography (OCT) based physiological monitor. An algorithm correlates OCT-based estimated blood analyte data with actual blood analyte data determined by other methods, such as invasively. OCT-based data is fit to the obtained blood analyte measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood analyte levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based physiological monitor can be calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.

Method for data reduction and calibration of an OCT-based physiological monitor

A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.

Apparatus and method for creating a stable optical interface

An optical fiber interrogator for interrogating optical fiber that includes fiber Bragg gratings ('FBGs'). The interrogator includes a light source operable to emit phase coherent light, amplitude modulation circuitry optically coupled to the light source and operable to generate pulses from the light, and control circuitry communicatively coupled to the amplitude modulation circuitry that is configured to perform a method for interrogating the optical fiber. The method includes generating a pair of light pulses by using the amplitude modulation circuitry to modulate light output by the light source without splitting the light.

Optical interrogator for performing interferometry using Bragg gratings

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Macungie, PA, United States of America

Walter Jeffrey Shakespeare