Boehringer Mannheim Gmbh

Hoffmann-La Roche Inc.

Roche Diagnostics Gmbh

Other

Medigene Oncology Gmbh

Boehringer Mannheim Bmbh

Walter-Gunar Friebe

Otto-Henning Wilhelms

Wolfgang Kampe

Edgar Voss

Birgit Bossenmaier

Max Thiel

Androniki Roesch

Matthias Rueth

Gisbert Sponer

Wolfgang Schaumann

Wolfgang Bartsch

Ulrike Reiff

Thomas Friess

Werner Winter

Alfred Mertens

Lothar Kling

Carl H Ross

Erhard Reinholz

Wolfgang Von Der Saal

Werner Scheuer

Egon Roesch

Karl Dietmann

Bernd Muller-Beckmann

Helmut Michel

Fritz Wiedemann

Ulrich Tibes

Guy Georges

Klaus Strein

Hans-Willi Krell

Kurt Stach, Deceased

Angelika Esswein

Jurgen Mertin

Henning Wilhelms

Sabine Woelle

Christos Tsaklakidis

Wolfgang Schaefer

Joachim Dickhaut

Ralf Schumacher

Herbert Leinert

Karlheinz Stegmeier

Nikolaos Dimoudis

Thomas Von Hirschheydt

Erwin Boehm

Uwe Michaelis

Frank Grams

Liesel Doerge

Bernhard Goller

Hans-Peter Wolff

Irene Kolm

Birgit Masjost

Herbert Simon

Rainer Haag

Wolfgang Jenni

Erwin Bohm

Ulrike Leser

By Werner Plattner, Administrator

Liesel Dorge

Wolfgang Schafer

Robert Umminger

Bernhard Koenig

Marcel Linssen

Christian Geletneky

Bernhard Knipp

Erika Von Mullendorff

Androniki Roesch Nee Apostolides

The present invention provides the compounds of formula (I) their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Ether derivatives

The present invention provides the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Oxidized thioether derivatives

The present invention relates to the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, compositions containing such compounds and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.

Triazole derivatives

There are presented compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms thereof, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Arylazole derivatives, their manufacture and use as pharmaceutical agents

The present invention relates to novel oxazoles of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Oxazoles, their manufacture and use as pharmaceutical agents

The present invention provides the compounds of formula I-A their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Pentafluorosulfanyl compounds

Compounds of formula (I) are useful in the therapy and/or prevention of illnesses with known over-expression of receptor tyrosine kinases of the HER-family like HER-2 and EGFR (HER-1). Accordingly, these compounds are useful for the treatment of diseases such as cancer in humans or animals.

Aniline derivatives, their manufacture and use as pharmaceutical agents

The present invention 1 includes compounds of formula (I), and their pharmaceutically acceptable salts. These compounds are useful in the control or prevention of cancer.

Oxazole derivatives

The present invention provides compounds of formula (I): their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Diazine derivatives

Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Benzylether derivatives

The present invention relates to new amino alcohol derivatives, process for the production thereof and medicaments and reagents containing these compounds.

Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds

Objects of the present invention are the compounds of formula (I) formula (I),their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above compounds in the control or prevention of illnesses such as cancer.

Thioether derivatives

This invention provides novel azepane derivatives or pharmaceutically acceptable salts thereof, according to the general formula (I)wherein the symbols are defined in the specification, as well as processes for their manufacture. The compounds according to this invention possess anti-cell proliferation activity and show an increased plasma-stability.

Azepane derivatives

Thiazolidinecarboxyl acids

Amino alcohol derivatives, method of producing said derivatives and medicaments containing them

Growing community of inventors

Mannheim, Germany

Walter-Gunar Friebe