Novimmune Sa

Walter Ferlin

Greg Elson

Olivier Leger

Marie Kosco-Vilbois

Florence Guilhot

Nicolas Fischer

Limin Shang

Emmanuel Monnet

Susana Salgado-Pires

This invention provides fully human monoclonal antibodies that recognize the IL-6/IL-6R complex. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.

Anti-IL-6/IL-6R antibodies and methods of use thereof

This invention relates generally to anti-Toll-like Receptor 4 (TLR4 antagonists) including antibodies that specifically bind Toll-like Receptor 4 (TLR-4), to methods of using the anti-TLR4 antagonists as therapeutics and to methods of using the anti-TLR4 antagonists for inhibiting, delaying the progression of, or otherwise ameliorating a symptom of Graft-versus-Host disease (GvHD) and/or improving survival of GvHD subjects and/or transplanted biological materials in subjects.

Anti&#x2014;TLR4 antibodies and methods of use thereof

Anti-IL-6/IL-6R antibodies

The invention relates to fully human antibodies, and fragments thereof, that bind to human interferon gamma (hIFN&#x3b3;), thereby modulating the interaction between IFN&#x3b3; and its receptor, IFN&#x3b3;-R, and/or modulating the biological activities of IFN&#x3b3;. The invention also relates to the use of such anti-IFN&#x3b3; antibodies in the prevention or treatment of immune-related disorders and in the amelioration of a symptom associated with an immune-related disorder.

Anti-interferon gamma antibodies and methods of use thereof

Methods of treating autoimmune diseases using anti-IL6/IL-6R complex antibodies

Anti-IL6/IL-6R antibodies

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Saint Cergues, France

Walter Ferlin