Heinrich Mack Nachf

Pfizer Corporation

Walter F Fries

Gunther F Pfaff

Jorg C Pfitzner

Gerhard Simon

This invention relates to pharmaceutical compositions for rectal administration containing semi-synthetic glycerides produced by interesterification, and, as the active ingredient, triazole derivatives of the formula ##STR1## wherein R.sup.1 is phenyl optionally sustituted with from one to three substituents independently selected from the group consisting of F, Cl, Br, I, CF.sub.3,(C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, and 5-chloropyrid-2-yl; X is OH, F, Cl or Br; R.sub.2 is H.sub.2, CH.sub.3 or F; and R.sub.3 is H or F.

Pharmaceutical compositions containing triazole derivatives for rectal

A pharmaceutical preparation for parenteral administration of a drug consisting of a solvent system containing:

Pharmaceutical preparations

Stable aqueous solutions of piroxicam suitable for pharmaceutical use are disclosed. These solutions all contain piroxicam in conjunction with a sub-stoichiometric amount of D-(-)-N-methylglucamine and have proplyene glycol, ethanol and water as the solvent, with the pH of said solutions being in the range of from about pH 8 to about pH 9. These particular pharmaceutical compositions possess excellent chemical stability properties and are especially suitable for parenteral administration.

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Illertissen, Germany

Walter F Fries