American Cyanamid Company

Walter E Meyer

Andrew S Tomcufcik

John P Dusza

Shin S Tseng

Joseph W Marsico, Jr

Nancy H Eudy

Peter S Chan

David L Crandall

William B Wright, Jr

Omega-((hetero)alkyl)benz(cd)indol-2-amines useful in inhibition of thromboxane synthetase and in treatment of hypertension in warm-blooded animals are disclosed.

Omega-((hetero)alkyl)benz(cd)-indol-2-amines

N.sup.1 substituted benz [cd] indol -2(1H)-imines useful as inhibitors of Thromboxane synthetase enzyme, hypertension and arrhythmia are described.

N.sup.1 -substituted benz(cd)indol-2-imine compounds as cardiovascular

This disclosure describes novel esters of (triarylphosphoranylidene)carbamic acid which are useful as diuretic agents.

Esters of (triarylphosphoranylidene)carbamic acid for effecting diuresis

N-[(1H-imidazol-1-yl)alkyl]benz[cd]-indol-2 amines useful as inhibitors of thromboxane synthetase enzyme, hypotensive agents and cardioprotective agents are described.

N-[(1H-imidazol-1-yl)alkyl]benz[cd]-indol-2-amines and use in inhibiting

This disclosure describes novel 2-(4-substituted-1-piperazinyl)[1,2,4]triazolo[1,5-a]pyrimidines useful as hypotensive agents.

2-(substituted-1-piperazinyl)[1,2,4]triazolo[1,5-a]pyrimidines

This disclosure describes certain pyrazolo[1,5-a]pyrimidines useful as hypotensive and/or anxiolytic agents, or as agents for the treatment of cognitive and related neural behavioral problems in mammals.

Pyrazolo[1,5-a]pyrimidines

This disclosure describes novel pyrazolylpiperazines useful as hypotensive agents in mammals and as intermediates for the preparation of certain pyrazolo[1,5-a]pryrimidines.

Pyrazolylpiperazines

This disclosure describes novel substituted 2-(pyridyl)imidazol-4-yl ketones and derivatives thereof which possess activity as hypotensive agents.

2-(Pyridyl)imidazolyl ketones

This disclosure describes novel 1-(5-amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines which are useful as hypotensive agents in mammals.

1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines

This disclosure describes novel N'-[2,6-dichloro-4-(substituted-benzylamino)phenyl]-N,N-dimethyl-formamidi nes which possess activity as hypotensive agents and as diuretics.

N'-(2,

This disclosure describes novel N'-[2,6-dichloro-4-(substituted-benzylideneamino)phenyl]-N,N-dimethylforma midines which possess activity as hypotensive agents and as diuretics.

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Suffern, NY, United States of America

Walter E Meyer