Basf Aktiengesellschaft

Walter Boell

Horst Koenig

Heinrich Adolphi

Karl Kiehs

Dieter Lenke

Gerda Von Philipsborn

Gerd-Ulrich Schwarz

Ulrich Schoellkopf

Hans-Joachim May

Hans-Heinrich Hausberg

4-.alpha.-Amino-arylmethyl-6-methyl-1,3-dihydro-furo[3,4-c]pyridin-7-ols of the formula ##STR1## where R.sup.1 and R.sup.2 together are alkylene which may be interrupted by a hetero-atom and may be substituted by C.sub.1-4 -alkyl, and

4-.alpha.-Amino-arylmethyl-6-methyl-1,3-dihydro-furo[3,4-c]pyridin-7-ols

Substituted 2,3-dihydrobenzofurylmethyl esters of the formula I ##STR1## where R.sup.8 is hydrogen or alkyl of up to 5 carbon atoms, R.sup.9 is alkyl, haloalkenyl or haloalkynyl, each of up to 5 carbon atoms,

Substituted 2,3-dihydrobenzofurylmethyl esters, their use in pest

Chirally substituted 2-imidazolin-5-ones and their use as intermediates for the preparation of optically active aminoacids, especially of optically active .alpha.-substituted aminoacids.

Chirally substituted 2-imidazolin-5-ones

New pyridinyl aminoalkyl ethers, their N-oxides and their physiologically acceptable addition salts with acids, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful in the treatment of cardiac arrhythmias.

Pyridinyl aminoalkyl ethers

New pyridin-3-ols and their N-oxides and acid addition salts, which are useful as intermediates, especially for the preparation of pharmacologically active compounds, and their preparation.

Pyridin-3-ols

An industrially advantageous process for the manufacture of vitamin B6 (pyridoxin) from 2-methyl-3-hydroxy-4,5-bis-(halomethyl)-pyridine, wherein the starting compound is first converted in the conventional manner to the corresponding pure acetoxy compound which is reacted with an alkali metal acetate, alkaline earth metal acetate or tertiary ammonium acetate to give pyridoxin triacetate, from which pyridoxin can be liberated by hydrolysis or trans-esterification.

Manufacture of pyridoxin

4-Methyloxazole is manufactured by reaction of formimido-esters with hydroxyacetone. 4-Methyloxazole, manufactured by the process of the invention, is a starting material for the manufacture of dyes, pharmaceuticals, pesticides and vitamins.

Manufacture of 4-methyloxazole

A process for the manufacture of .beta.-bromoalkylsulfones and .beta.-bromoalkenylsulfones by addition reaction of sulfonic acid bromides with olefins or acetylenes in the presence of hydroperoxide and, optionally, of metal salts. Starting materials for further syntheses and for biologically active compounds may be obtained by subsequent dehydrobromination of the addition products.

Growing community of inventors

Dannstadt-Schauernheim, Germany

Walter Boell